An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.
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Mst1-FoxO signaling protects Naïve T lymphocytes from cellular oxidative stress in miceAkt and mTOR in B Cell Activation and DifferentiationMetabolic regulation of T cell differentiation and functionCellular and molecular determinants for the development of natural and induced regulatory T cellsFOXO transcription factors throughout T cell biologyHIV restriction in quiescent CD4⁺ T cellsRedox regulation of SIRT1 in inflammation and cellular senescenceA New Murine Model for Gastrointestinal Anthrax InfectionMetabolic maintenance of cell asymmetry following division in activated T lymphocytesKAP1 regulates gene networks controlling T-cell development and responsiveness.Mechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer ImmunotherapySignaling by the phosphoinositide 3-kinase family in immune cellsIdentification of a common lupus disease-associated microRNA expression pattern in three different murine models of lupusEx vivo modulation of the Foxo1 phosphorylation state does not lead to dysfunction of T regulatory cells.Novel Foxo1-dependent transcriptional programs control T(reg) cell functionInterleukin-7 and Immunosenescence.FOXO transcription factors: their clinical significance and regulation.Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cellsMemory CD8+ T cell differentiationPPARγ negatively regulates T cell activation to prevent follicular helper T cells and germinal center formation.Foxo transcription factors control regulatory T cell development and functionVasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels.Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cellsEarly events governing memory CD8+ T-cell differentiation.Tenuous paths in unexplored territory: From T cell receptor signaling to effector gene expression during thymocyte selection.Cutting edge: Expression of the transcription factor E74-like factor 4 is regulated by the mammalian target of rapamycin pathway in CD8+ T cells.TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice.A CD4+ T cell antagonist epitope down-regulates activating signaling proteins, up-regulates inhibitory signaling proteins and abrogates HIV-specific T cell function.Highly specialized role of Forkhead box O transcription factors in the immune system.Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.Foxo: in command of T lymphocyte homeostasis and tolerance.The transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infectionMicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases.Ets-1 maintains IL-7 receptor expression in peripheral T cells.Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis.TSLP enhances the function of helper type 2 cellsThe human T-cell leukemia virus type 1 oncoprotein tax controls forkhead box O4 activity through degradation by the proteasomeCdc25A regulates matrix metalloprotease 1 through Foxo1 and mediates metastasis of breast cancer cells.The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.
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An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
An essential role of the Forkh ...... ell homeostasis and tolerance.
@en
An essential role of the Forkh ...... ell homeostasis and tolerance.
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type
label
An essential role of the Forkh ...... ell homeostasis and tolerance.
@en
An essential role of the Forkh ...... ell homeostasis and tolerance.
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prefLabel
An essential role of the Forkh ...... ell homeostasis and tolerance.
@en
An essential role of the Forkh ...... ell homeostasis and tolerance.
@nl
P2093
P2860
P1433
P1476
An essential role of the Forkh ...... ell homeostasis and tolerance.
@en
P2093
Omar Beckett
Richard A Flavell
Weiming Ouyang
P2860
P304
P356
10.1016/J.IMMUNI.2009.02.003
P407
P577
2009-03-12T00:00:00Z