Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer - Wikidata - awgldk - TriplyDB

Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer

Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer

http://www.wikidata.org/entity/Q37219070

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Synthetic glycolipid activators of natural killer T cells as immunotherapeutic agents Turned on by danger: activation of CD1d-restricted invariant natural killer T cells Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V 14i NKT Cells A Molecular Basis for the Exquisite CD1d-Restricted Antigen Specificity and Functional Responses of Natural Killer T Cells Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.Structural Basis for the Recognition of C20:2-αGalCer by the Invariant Natural Killer T Cell Receptor-like Antibody L363 Structural and Functional Characterization of a Novel Nonglycosidic Type I NKT Agonist with Immunomodulatory Properties Enhanced TCR Footprint by a Novel Glycolipid Increases NKT-Dependent Tumor Protection Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor An in silico approach for modelling T-helper polarizing iNKT cell agonists Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury Mechanisms of inflammatory responses in obese adipose tissue.Reciprocal Crosstalk between Dendritic Cells and Natural Killer T Cells: Mechanisms and Therapeutic Potential.Lipid and glycolipid antigens of CD1d-restricted natural killer T cells.Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents The effect of intracellular trafficking of CD1d on the formation of TCR repertoire of NKT cells.Development of spontaneous anergy in invariant natural killer T cells in a mouse model of dyslipidemia.Human gamma delta T cells: Evolution and ligand recognition.Distinct APCs explain the cytokine bias of α-galactosylceramide variants in vivo.Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity.The structural and functional role of myelin fast-migrating cerebrosides: pathological importance in multiple sclerosis.Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4.Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes Scavenger receptors target glycolipids for natural killer T cell activation.Invariant natural killer T cells: bridging innate and adaptive immunity.Recognition of CD1d-restricted antigens by natural killer T cells.Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine.Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens.Targeting the diverse immunological functions expressed by hepatic NKT cells.NKT cell ligand recognition logic: molecular basis for a synaptic duet and transmission of inflammatory effectors.Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells.Invariant natural killer T cells in adipose tissue: novel regulators of immune-mediated metabolic disease.Lactic acid in tumor microenvironments causes dysfunction of NKT cells by interfering with mTOR signaling.Glycolipid activators of invariant NKT cells as vaccine adjuvants.Donor-unrestricted T cells in the human CD1 system.Selective Conditions Are Required for the Induction of Invariant NKT Cell Hyporesponsiveness by Antigenic Stimulation.Endogenous lipid antigens for invariant Natural Killer T cells hold the reins in adipose tissue homeostasis.Synthesis and evaluation of amino-modified alpha-GalCer analogues.

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Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer

http://www.wikidata.org/entity/Q37219070

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 08 June 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Lysosomal recycling terminates ...... cell lipid antigen alphaGalCer

@en

Lysosomal recycling terminates ...... ell lipid antigen alphaGalCer.

@nl

type

label

Lysosomal recycling terminates ...... cell lipid antigen alphaGalCer

@en

Lysosomal recycling terminates ...... ell lipid antigen alphaGalCer.

@nl

altLabel

Lysosomal recycling terminates ...... NKT cell lipid antigen GalCer

@en

prefLabel

Lysosomal recycling terminates ...... cell lipid antigen alphaGalCer

@en

Lysosomal recycling terminates ...... ell lipid antigen alphaGalCer.

@nl

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PNAS.0901228106

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Lysosomal recycling terminates ...... cell lipid antigen alphaGalCer

@en

P2093

Albert Bendelac

http://www.w3.org/2001/XMLSchema#string

Karl O A Yu

http://www.w3.org/2001/XMLSchema#string

Li Bai

http://www.w3.org/2001/XMLSchema#string

Luc Teyton

http://www.w3.org/2001/XMLSchema#string

Paul B Savage

http://www.w3.org/2001/XMLSchema#string

Stefan Freigang

http://www.w3.org/2001/XMLSchema#string

Yang Liu

http://www.w3.org/2001/XMLSchema#string

Yuval Sagiv

http://www.w3.org/2001/XMLSchema#string

P2860

Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor

CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor

Apolipoprotein-mediated pathways of lipid antigen presentation

The biology of NKT cells

CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain

Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d molecules.

Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides.

Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells.

Intracellular pathways of CD1 antigen presentation.

P304

10254-10259

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scholarly article

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10.1073/PNAS.0901228106

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P407

P433

25

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106

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Steven A Porcelli

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2009-06-08T00:00:00Z

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26275961

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19506241

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2693181

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