Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
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Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDFCurcumin AntiCancer Studies in Pancreatic CancerInherited pancreatic cancer syndromesEpigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?Natural Compounds Modulating Mitochondrial FunctionsDietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cellsMolecular targets of isothiocyanates in cancer: recent advancesPancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.Extracellular signal-regulated kinase signaling-mediated induction and interaction of FOXO3a and p53 contribute to the inhibition of nasopharyngeal carcinoma cell growth by curcuminExperimental therapy of ovarian cancer with synthetic makaluvamine analog: in vitro and in vivo anticancer activity and molecular mechanisms of action.Therapeutic applications of curcumin for patients with pancreatic cancer.Activation of checkpoint kinase 2 by 3,3'-diindolylmethane is required for causing G2/M cell cycle arrest in human ovarian cancer cells.Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells.ATM signalling and cancer.Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage.Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells.HER2 mediated de novo production of TGFβ leads to SNAIL driven epithelial-to-mesenchymal transition and metastasis of breast cancerPiperlongumine induces pancreatic cancer cell death by enhancing reactive oxygen species and DNA damageCurcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells.Metastasis of Breast Tumor Cells to Brain Is Suppressed by Phenethyl Isothiocyanate in a Novel In Vivo Metastasis Model.Zygotic G2/M cell cycle arrest induced by ATM/Chk1 activation and DNA repair in mouse embryos fertilized with hydrogen peroxide-treated epididymal mouse sperm.Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation.Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy.Genomic profiling guides the choice of molecular targeted therapy of pancreatic cancer.Quercetin-3-methyl ether inhibits lapatinib-sensitive and -resistant breast cancer cell growth by inducing G(2)/M arrest and apoptosis.Pancreatic cancer chemoprevention by phytochemicalsNano-curcumin inhibits proliferation of esophageal adenocarcinoma cells and enhances the T cell mediated immune response.Pyridine analogues of curcumin exhibit high activity for inhibiting CWR-22Rv1 human prostate cancer cell growth and androgen receptor activation.Relationships between cell cycle pathway gene polymorphisms and risk of hepatocellular carcinomaCurcumin and cancer cells: how many ways can curry kill tumor cells selectively?Curcumin binds tubulin, induces mitotic catastrophe, and impedes normal endothelial cell proliferation.Big punches come in nanosizes for chemoprevention.Dietary flavonoids as cancer prevention agents.Therapeutic potential of curcumin in gastrointestinal diseases.Curcumin in various cancers.Curcuma Contra Cancer? Curcumin and Hodgkin's Lymphoma.Plant natural products: from traditional compounds to new emerging drugs in cancer therapy.Activation and Inhibition of ATM by Phytochemicals: Awakening and Sleeping the Guardian Angel Naturally.Inhibition of Cell Survival by Curcumin Is Associated with Downregulation of Cell Division Cycle 20 (Cdc20) in Pancreatic Cancer Cells.Therapeutic Potential of Curcumin in Treatment of Pancreatic Cancer: Current Status and Future Perspectives.
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Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Activation of ATM/Chk1 by curc ...... human pancreatic cancer cells
@en
Activation of ATM/Chk1 by curc ...... human pancreatic cancer cells.
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type
label
Activation of ATM/Chk1 by curc ...... human pancreatic cancer cells
@en
Activation of ATM/Chk1 by curc ...... human pancreatic cancer cells.
@nl
prefLabel
Activation of ATM/Chk1 by curc ...... human pancreatic cancer cells
@en
Activation of ATM/Chk1 by curc ...... human pancreatic cancer cells.
@nl
P2093
P2860
P356
P1476
Activation of ATM/Chk1 by curc ...... human pancreatic cancer cells
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.BJC.6605039
P407
P577
2009-05-01T00:00:00Z