Cell cycle checkpoint signaling through the ATM and ATR kinases
about
Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replicationChemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicinHuman single-stranded DNA binding proteins are essential for maintaining genomic stabilityMicroRNAs in the DNA Damage/Repair Network and CancerStructural basis of γH2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathwayPML regulates p53 stability by sequestering Mdm2 to the nucleolusUSP10 regulates p53 localization and stability by deubiquitinating p53Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repairHuman Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpointIdentification and characterization of human MUS81-MMS4 structure-specific endonucleaseFas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosisPhosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damageMSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylationSUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damageDNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilizationInteraction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cellsNek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responsesThe DNA damage pathway regulates innate immune system ligands of the NKG2D receptorDNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domainsProteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stressHow cells switch HIPK2 on and offThe F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stressInteraction between human MCM7 and Rad17 proteins is required for replication checkpoint signalingMolecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testisChk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genesHuman Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpointCdc5L interacts with ATR and is required for the S-phase cell-cycle checkpointMiz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damageInduction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stressThe cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repairATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylationUV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalizationChromosomal instability at common fragile sites in Seckel syndromeHaploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cellsElucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitroMethylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint responseHuman Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint
P2860
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P2860
Cell cycle checkpoint signaling through the ATM and ATR kinases
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Cell cycle checkpoint signaling through the ATM and ATR kinases
@ast
Cell cycle checkpoint signaling through the ATM and ATR kinases
@en
type
label
Cell cycle checkpoint signaling through the ATM and ATR kinases
@ast
Cell cycle checkpoint signaling through the ATM and ATR kinases
@en
prefLabel
Cell cycle checkpoint signaling through the ATM and ATR kinases
@ast
Cell cycle checkpoint signaling through the ATM and ATR kinases
@en
P3181
P356
P1433
P1476
Cell cycle checkpoint signaling through the ATM and ATR kinases
@en
P2093
Abraham RT
P304
P3181
P356
10.1101/GAD.914401
P407
P577
2001-09-01T00:00:00Z