Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus.
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Beyond the monoaminergic hypothesis: neuroplasticity and epigenetic changes in a transgenic mouse model of depressionLoss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalitiesRett Syndrome: Crossing the Threshold to Clinical TranslationGenes, circuits, and precision therapies for autism and related neurodevelopmental disordersMECP2 disorders: from the clinic to mice and backCytosine modifications in neurodevelopment and diseasesRole of mecp2 in experience-dependent epigenetic programmingReversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides.Rett syndrome - biological pathways leading from MECP2 to disorder phenotypesA review of Rett syndrome (RTT) with induced pluripotent stem cellsCrh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndromeAtaxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discoveryVPA alleviates neurological deficits and restores gene expression in a mouse model of Rett syndromeInvolvement of MeCP2 in Regulation of Myelin-Related Gene Expression in Cultured Rat OligodendrocytesInfluenza A induces dysfunctional immunity and death in MeCP2-overexpressing mice.Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome.The cerebellum, sensitive periods, and autism.Mild expression differences of MECP2 influencing aggressive social behavior.A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapyMeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain.The Crucial Role of DNA Methylation and MeCP2 in Neuronal FunctionGlobal transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons.MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5.Mecp2 Mediates Experience-Dependent Transcriptional Upregulation of Ryanodine Receptor Type-3.Experimental Autoimmune Encephalomyelitis (EAE)-Induced Elevated Expression of the E1 Isoform of Methyl CpG Binding Protein 2 (MeCP2E1): Implications in Multiple Sclerosis (MS)-Induced Neurological Disability and Associated Myelin DamageRett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice.Lossless 3-D reconstruction and registration of semi-quantitative gene expression data in the mouse brain.MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice.Cell-autonomous alterations in dendritic arbor morphology and connectivity induced by overexpression of MeCP2 in Xenopus central neurons in vivoGenome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndromeA mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmissionGenome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes.Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain.MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line.Disruption of DNA-methylation-dependent long gene repression in Rett syndrome.Astrocyte-specific regulation of hMeCP2 expression in Drosophila.5-Hydroxymethylcytosine: a stable or transient DNA modification?Pubertal development in Rett syndrome deviates from typical females
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Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 15 April 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mouse models of MeCP2 disorder ...... e cerebellum and hypothalamus.
@en
Mouse models of MeCP2 disorder ...... e cerebellum and hypothalamus.
@nl
type
label
Mouse models of MeCP2 disorder ...... e cerebellum and hypothalamus.
@en
Mouse models of MeCP2 disorder ...... e cerebellum and hypothalamus.
@nl
prefLabel
Mouse models of MeCP2 disorder ...... e cerebellum and hypothalamus.
@en
Mouse models of MeCP2 disorder ...... e cerebellum and hypothalamus.
@nl
P2860
P50
P356
P1476
Mouse models of MeCP2 disorder ...... e cerebellum and hypothalamus.
@en
P2093
Christina Thaller
Shay Ben-Shachar
P2860
P304
P356
10.1093/HMG/DDP181
P577
2009-04-15T00:00:00Z