MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice.
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A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.p39 Is Responsible for Increasing Cdk5 Activity during Postnatal Neuron Differentiation and Governs Neuronal Network Formation and Epileptic ResponsesA critical and cell-autonomous role for MeCP2 in synaptic scaling upMicroglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expressionMechanisms of Functional Hypoconnectivity in the Medial Prefrontal Cortex of Mecp2 Null Mice.Beyond Widespread Mecp2 Deletions to Model Rett Syndrome: Conditional Spatio-Temporal Knockout, Single-Point Mutations and Transgenic Rescue MiceMapping pathological phenotypes in a mouse model of CDKL5 disorderNeuroanatomy in mouse models of Rett syndrome is related to the severity of Mecp2 mutation and behavioral phenotypes.Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling.Dendritic spine dysgenesis in Rett syndrome.Genotype-specific effects of Mecp2 loss-of-function on morphology of Layer V pyramidal neurons in heterozygous female Rett syndrome model mice.Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital.Applying the ethoexperimental approach to neurodevelopmental syndrome research reveals exaggerated defensive behavior in Mecp2 mutant mice.Regulatory functions and pathological relevance of the MECP2 3'UTR in the central nervous system.Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction.Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domainNeuronal morphology in MeCP2 mouse models is intrinsically variable and depends on age, cell type, and Mecp2 mutation.Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations.Dendritic arborization and spine dynamics are abnormal in the mouse model of MECP2 duplication syndrome.Distinct Defects in Spine Formation or Pruning in Two Gene Duplication Mouse Models of Autism.Importance of gene dosage in controlling dendritic arbor formation during development.Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models.Autism spectrum disorder: neuropathology and animal models.Axonal and subcellular labelling using modified rabies viral vectors.Fundamental Elements in Autism: From Neurogenesis and Neurite Growth to Synaptic Plasticity.Activation of the Medial Prefrontal Cortex Reverses Cognitive and Respiratory Symptoms in a Mouse Model of Rett SyndromeSite-directed RNA repair of endogenous Mecp2 RNA in neurons.Structural and functional differences in the barrel cortex of Mecp2 null mice.Heterozygous deletion of the Williams-Beuren syndrome critical interval in mice recapitulates most features of the human disorder.
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MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice.
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2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@ast
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@en
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@nl
type
label
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@ast
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@en
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@nl
prefLabel
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@ast
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@en
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@nl
P2093
P2860
P1433
P1476
MeCP2 mutation results in comp ...... ortical neurons of YFP-H mice.
@en
P2093
David B Levin
David P Stuss
Jamie D Boyd
Kerry R Delaney
P2860
P304
P356
10.1371/JOURNAL.PONE.0031896
P407
P577
2012-03-07T00:00:00Z