Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9. - Wikidata - awgldk - TriplyDB

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

http://www.wikidata.org/entity/Q37223664

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CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases Engineering large animal models of human disease CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's Disease Targeted genome editing in primate embryos Genome Editing and Muscle Stem Cells as a Therapeutic Tool for Muscular Dystrophies.Progress and prospects of gene therapy clinical trials for the muscular dystrophies.Applications of CRISPR technologies in research and beyond.Application of CRISPR/Cas9 for biomedical discoveries.The societal opportunities and challenges of genome editing.Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body Sites of retroviral DNA integration: From basic research to clinical applications Prospect of gene therapy for cardiomyopathy in hereditary muscular dystrophy.Application of the genome editing tool CRISPR/Cas9 in non-human primates.Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9.Genome editing: progress and challenges for medical applications.Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos Germ line genome editing in clinics: the approaches, objectives and global society.Non-human Primate Models for Brain Disorders - Towards Genetic Manipulations via Innovative Technology.Viral vector-mediated gene therapies.Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies.CRISPR Editing in Biological and Biomedical Investigation.Current Progress in Therapeutic Gene Editing for Monogenic Diseases Homology-mediated end joining-based targeted integration using CRISPR/Cas9.Assisted reproductive technologies in the common marmoset: an integral species for developing nonhuman primate models of human diseases.Genome editing in nonhuman primates: approach to generating human disease models.Quantitative assessment of timing, efficiency, specificity and genetic mosaicism of CRISPR/Cas9-mediated gene editing of hemoglobin beta gene in rhesus monkey embryos.Opportunities and challenges in modeling human brain disorders in transgenic primates.The big bang of genome editing technology: development and application of the CRISPR/Cas9 system in disease animal models Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases.Cornerstones of CRISPR-Cas in drug discovery and therapy.Non-human primate models of PD to test novel therapies.Use of CRISPR/Cas9 to model brain diseases.Rhesus iPSC Safe Harbor Gene-Editing Platform for Stable Expression of Transgenes in Differentiated Cells of All Germ Layers.One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.Nonhuman Primates: A Vital Model for Basic and Applied Research on Female Reproduction, Prenatal Development, and Women's Health.Genome engineering: a new approach to gene therapy for neuromuscular disorders.Correction of the Exon 2 Duplication in DMD Myoblasts by a Single CRISPR/Cas9 System.A Perspective on the State of Genome Editing.Vitrification of Rhesus Macaque Mesenchymal Stem Cells and the Effects on Global Gene Expression.

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Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

http://www.wikidata.org/entity/Q37223664

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 09 April 2015

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

@en

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

@nl

type

label

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

@en

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

@nl

prefLabel

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

@en

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

@nl

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Human Molecular Genetics

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Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9

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Chenyang Si

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Hong Wang

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Ruxiao Xing

http://www.w3.org/2001/XMLSchema#string

Shang-Hsun Yang

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Shihua Li

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Weili Yang

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Xiangyu Guo

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Xiao-Jiang Li

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Xiuqiong Pu

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Yinghui Zheng

http://www.w3.org/2001/XMLSchema#string

P2860

Development and applications of CRISPR-Cas9 for genome engineering.

X chromosome-linked muscular dystrophy (mdx) in the mouse

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Dystrophin: the protein product of the Duchenne muscular dystrophy locus

Genetic engineering of human pluripotent cells using TALE nucleases

Timely translation during the mouse oocyte-to-embryo transition.

TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys.

Dystrophin and mutations: one gene, several proteins, multiple phenotypes.

Mammalian models of Duchenne Muscular Dystrophy: pathological characteristics and therapeutic applications.

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3764-3774

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scholarly article

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10.1093/HMG/DDV120

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24

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2015-04-09T00:00:00Z

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25859012

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