Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis. - Wikidata - awgldk - TriplyDB

Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis.

Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis.

http://www.wikidata.org/entity/Q37224388

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Pharmacotherapy of systemic sclerosis Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo Lysophospholipid receptors in drug discovery.A metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritis Reduction in serum sphingosine 1-phosphate concentration in malaria.A clean-up technology for the simultaneous determination of lysophosphatidic acid and sphingosine-1-phosphate by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a phosphate-capture molecule, Phos-tag.LPA receptor signaling: pharmacology, physiology, and pathophysiology.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Lysophosphatidic acid-activated Cl- current activity in human systemic sclerosis skin fibroblasts Aiming drug discovery at lysophosphatidic acid targets.Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation Experimentally-derived fibroblast gene signatures identify molecular pathways associated with distinct subsets of systemic sclerosis patients in three independent cohorts.Vascular involvement in systemic sclerosis (scleroderma).Evaluation of 11C-acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma.Pathogenesis of Systemic Sclerosis.Dual Action of Lysophosphatidate-Functionalised Titanium: Interactions with Human (MG63) Osteoblasts and Methicillin Resistant Staphylococcus aureus.Clopidogrel treatment may associate with worsening of endothelial function and development of new digital ulcers in patients with systemic sclerosis: results from an open label, proof of concept study Generation of N-acylphosphatidylethanolamine by members of the phospholipase A/acyltransferase (PLA/AT) family.Shaping the landscape: metabolic regulation of S1P gradients.Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.Sphingosine-1-phosphate: a potential therapeutic target for rheumatoid arthritis.Lysophosphatidic acid-1-receptor targeting agents for fibrosis.Sphingolipid regulation of tissue fibrosis Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications.Review: Frontiers of Antifibrotic Therapy in Systemic Sclerosis.Protein Tyrosine Phosphatases in Systemic Sclerosis: Potential Pathogenic Players and Therapeutic Targets.Reduced kidney levels of lysophosphatidic acids in rats after chronic administration of aristolochic acid: Its possible protective role in renal fibrosis Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma.Miltefosine: a novel internal standard approach to lysophospholipid quantitation using LC-MS/MS.Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study.Possible role of lysophosphatidic acid in rat model of hypoxic pulmonary vascular remodeling.FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin.An Autotaxin/Lysophosphatidic Acid/Interleukin-6 Amplification Loop Drives Scleroderma Fibrosis.Antifibrotic effect of lysophosphatidic acid receptors LPA1 and LPA3 antagonist on experimental murine scleroderma induced by bleomycin.

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Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis.

http://www.wikidata.org/entity/Q37224388

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Elevated serum levels of arach ...... osphate in systemic sclerosis.

@en

Elevated serum levels of arach ...... osphate in systemic sclerosis.

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type

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Elevated serum levels of arach ...... osphate in systemic sclerosis.

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Elevated serum levels of arach ...... osphate in systemic sclerosis.

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prefLabel

Elevated serum levels of arach ...... osphate in systemic sclerosis.

@en

Elevated serum levels of arach ...... osphate in systemic sclerosis.

@nl

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International Journal of Medical Sciences

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Elevated serum levels of arach ...... osphate in systemic sclerosis.

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Akira Tokumura

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Arnold Postlethwaite

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Junichi Morishige

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Laura D Carbone

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Masaki Kikuchi

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Mitchell A Watsky

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Yasuko Yoshioka

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P2860

Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids

The myofibroblast: one function, multiple origins

Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure-activity relationship of cloned LPA receptors

Lysophospholipid receptors: signalling, pharmacology and regulation by lysophospholipid metabolism

Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity.

Beta thromboglobulin and platelet factor 4 in bronchoalveolar lavage fluid of patients with systemic sclerosis

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168-176

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10.7150/IJMS.6.168

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19521548

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2695151

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