Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy
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Myocardial autophagic energy stress responses--macroautophagy, mitophagy, and glycophagyChronic high fat diet induces cardiac hypertrophy and fibrosis in mice.Role of autophagy in metabolic syndrome-associated heart disease.CREG1 heterozygous mice are susceptible to high fat diet-induced obesity and insulin resistance.Akt2 knockout alleviates prolonged caloric restriction-induced change in cardiac contractile function through regulation of autophagy.Metabolic control of autophagyProtein tyrosine phosphatase 1B and insulin resistance: role of endoplasmic reticulum stress/reactive oxygen species/nuclear factor kappa B axis.Autophagy: a housekeeper in cardiorenal metabolic health and diseaseLipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activityMyocardial mitochondrial and contractile function are preserved in mice lacking adiponectin.Perivascular adipose tissue-derived adiponectin inhibits collar-induced carotid atherosclerosis by promoting macrophage autophagy.Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathyDefective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy.Hyperglycemia stimulates p62/PKCζ interaction, which mediates NF-κB activation, increased Nox4 expression, and inflammatory cytokine activation in vascular smooth muscleACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity.Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor.Berberine improves mesenteric artery insulin sensitivity through up-regulating insulin receptor-mediated signalling in diabetic ratsEarly administration of trimetazidine attenuates diabetic cardiomyopathy in rats by alleviating fibrosis, reducing apoptosis and enhancing autophagyMiR-129-5p-mediated Beclin-1 suppression inhibits endothelial cell autophagy in atherosclerosis.The role of autophagy in cardiac hypertrophy.Is the lack of adiponectin associated with increased ER/SR stress and inflammation in the heart?Mammalian target of rapamycin signaling in cardiac physiology and disease.Cardiac metabolism and its interactions with contraction, growth, and survival of cardiomyocytes.Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease.Boosting autophagy in the diabetic heart: a translational perspective.Regulatory role of autophagy in globular adiponectin-induced apoptosis in cancer cells.AMPK in Cardiovascular Diseases.Targeting the energy guardian AMPK: another avenue for treating cardiomyopathy?Insights for Oxidative Stress and mTOR Signaling in Myocardial Ischemia/Reperfusion Injury under Diabetes.Myocardial stress and autophagy: mechanisms and potential therapies.Diabetic Cardiomyopathy: Current Approach and Potential Diagnostic and Therapeutic Targets.Cathepsin K knockout protects against cardiac dysfunction in diabetic mice.Adiponectin attenuates profibrotic extracellular matrix remodeling following cardiac injury by up-regulating matrix metalloproteinase 9 expression in mice.Cardiac proteasome functional insufficiency plays a pathogenic role in diabetic cardiomyopathy.Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling.Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer.Activation of IGF-1 receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice.Adiponectin deficiency rescues high-fat diet-induced hepatic injury, apoptosis and autophagy loss despite persistent steatosis.The effects of fatty acid composition on cardiac hypertrophy and function in mouse models of diet-induced obesity.[Autophagy in the cardiovascular system].
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Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 21 March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Adiponectin knockout accentuat ...... dysfunction: role of autophagy
@en
Adiponectin knockout accentuat ...... ysfunction: role of autophagy.
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type
label
Adiponectin knockout accentuat ...... dysfunction: role of autophagy
@en
Adiponectin knockout accentuat ...... ysfunction: role of autophagy.
@nl
prefLabel
Adiponectin knockout accentuat ...... dysfunction: role of autophagy
@en
Adiponectin knockout accentuat ...... ysfunction: role of autophagy.
@nl
P2093
P2860
P1476
Adiponectin knockout accentuat ...... dysfunction: role of autophagy
@en
P2093
P2860
P304
P356
10.1016/J.BBADIS.2013.03.013
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P577
2013-03-21T00:00:00Z