Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma. - Wikidata - awgldk - TriplyDB

Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.

Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.

http://www.wikidata.org/entity/Q37235002

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ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6 Channelopathies Endoplasmic reticulum stress and the related signaling networks in severe asthma Airway smooth muscle in asthma: just a target for bronchodilation?Rhinovirus and childhood asthma: an update The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro Regulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma.Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.Ca(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model.Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells.β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D SERCA2 regulates non-CF and CF airway epithelial cell response to ozone Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.[Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma.Differential induction of CD38 expression by TNF-{alpha} in asthmatic airway smooth muscle cells.Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma.Targeted transgenesis identifies Gαs as the bottleneck in β2-adrenergic receptor cell signaling and physiological function in airway smooth muscle.Promoter characterization and role of cAMP/PKA/CREB in the basal transcription of the mouse ORMDL3 gene Activation of store-operated calcium entry in airway smooth muscle cells: insight from a mathematical model.Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells.Protease activated receptor-2 expression and function in asthmatic bronchial smooth muscle No evidence for altered intracellular calcium-handling in airway smooth muscle cells from human subjects with asthma A deterministic model predicts the properties of stochastic calcium oscillations in airway smooth muscle cells.Examination of the relationship between variation at 17q21 and childhood wheeze phenotypes.Mechanisms of Cigarette Smoke Effects on Human Airway Smooth Muscle.The calcium-sensing receptor: one of a kind.Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma.PPARγ Ligands Regulate Noncontractile and Contractile Functions of Airway Smooth Muscle: Implications for Asthma Therapy.Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration Phenotype, endotype and patient-specific computational modelling for optimal treatment design in asthma.Ryanodine receptor sensitization results in abnormal calcium signaling in airway smooth muscle cells.Effects of the inflammatory cytokines TNF-α and IL-13 on stromal interaction molecule-1 aggregation in human airway smooth muscle intracellular Ca(2+) regulation Airway smooth muscle in airway reactivity and remodeling: what have we learned?Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension.Polymorphisms of ATF6B Are Potentially Associated With FEV1 Decline by Aspirin Provocation in Asthmatics.Endoplasmic-reticulum calcium depletion and disease.Exploring lung physiology in health and disease with lung slices The pivotal role of airway smooth muscle in asthma pathophysiology cAMP regulation of airway smooth muscle function.Airway smooth muscle as a target in asthma and the beneficial effects of bronchial thermoplasty.

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Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.

http://www.wikidata.org/entity/Q37235002

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scientific article published on 16 June 2009

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Diminished sarco/endoplasmic r ...... modelling in bronchial asthma.

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Diminished sarco/endoplasmic reticulum Ca2+ ATPase

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Diminished sarco/endoplasmic r ...... modelling in bronchial asthma.

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Diminished sarco/endoplasmic reticulum Ca2+ ATPase

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Diminished sarco/endoplasmic r ...... modelling in bronchial asthma.

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Diminished sarco/endoplasmic reticulum Ca2+ ATPase

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PNAS.0902295106

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Proceedings of the National Academy of Sciences of the United States of America

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Diminished sarco/endoplasmic r ...... modelling in bronchial asthma.

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Brian J O'Connor

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Charlotta Karner

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Christopher J Corrigan

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Clare G McVicker

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David E Simcock

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Jeremy P T Ward

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K Fan Chung

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Katharina Mahn

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Mark R Holt

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Oluwaseun O Ojo

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P2860

Ca2+ homeostasis in Brody's disease. A study in skeletal muscle and cultured muscle cells and the effects of dantrolene an verapamil

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Molecular characterization of a sarco(endo)plasmic reticulum Ca2+-ATPase gene from Paramecium tetraurelia and localization of its gene product to sub-plasmalemmal calcium stores.

Phenotypic diversity and molecular mechanisms of airway smooth muscle proliferation in asthma.

Lamellipodial contractions during crawling and spreading

Modulation of calcium homeostasis as a mechanism for altering smooth muscle responsiveness in asthma.

Global strategy for asthma management and prevention: GINA executive summary.

Calcium pump isoforms: diversity, selectivity and plasticity. Review article.

Phenotypes of SERCA and PMCA knockout mice.

Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma

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10775-10780

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10.1073/PNAS.0902295106

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David J Cousins

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