about
Leukotriene E4 is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression.IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammationCharacterisation of P2Y(12) receptor responsiveness to cysteinyl leukotrienes.IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo.Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells.Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.IL-2 regulates expression of C-MAF in human CD4 T cellsIL-25/IL-33-responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa.Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production.Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.Therapeutic approaches for control of transcription factors in allergic disease.Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy.Fibronectin is a TH1-specific molecule in human subjects.Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment.T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex.Pinning allergies on pathogenic TH2 cells.Regulation of GM-CSF expression by the transcription factor c-Maf.Human group 2 innate lymphoid cells do not express the IL-5 receptor.Mucosal Type 2 Innate Lymphoid Cells Are a Key Component of the Allergic Response to Aeroallergens.Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy.CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.Redefinition of the cleavage sites of DNase I on the nucleosome core particle.DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation.Gene expression profiling of endobronchial ultrasound (EBUS)-derived cytological fine needle aspirates from hilar and mediastinal lymph nodes in non-small cell lung cancer.Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matterDifferential expression of functional chemokine receptors on human blood and lung group 2 innate lymphoid cellsDNase I footprinting of the human interleukin-5 gene promoterIntergenic transcription occurs throughout the human IL-4/IL-13 gene clusterChromatin structure and DNA methylation of the IL-4 gene in human T(H)2 cellsmiR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
David J Cousins
@ast
David J Cousins
@en
David J Cousins
@es
David J Cousins
@nl
type
label
David J Cousins
@ast
David J Cousins
@en
David J Cousins
@es
David J Cousins
@nl
prefLabel
David J Cousins
@ast
David J Cousins
@en
David J Cousins
@es
David J Cousins
@nl
P108
P106
P21
P31
P496
0000-0003-3821-9596