Modulation of virulence factors in Francisella tularensis determines human macrophage responses.
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Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokinesAdaptation of Francisella tularensis to the mammalian environment is governed by cues which can be mimicked in vitro.Global transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis.Francisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo.Large scale comparison of innate responses to viral and bacterial pathogens in mouse and macaque.Cytokines involved in interferon-gamma production by human macrophagesA Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacyGlycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in miceEvaluation of reference genes for reverse transcription quantitative PCR analyses of fish-pathogenic Francisella strains exposed to different growth conditions.Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity.A Francisella tularensis locus required for spermine responsiveness is necessary for virulence.Immunoproteomic profiling of Rickettsia parkeri and Rickettsia amblyommiiDevelopment of tolerogenic dendritic cells and regulatory T cells favors exponential bacterial growth and survival during early respiratory tularemia.Characterization and application of a glucose-repressible promoter in Francisella tularensisDirect and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.The intracellular environment of human macrophages that produce nitric oxide promotes growth of mycobacteria.MyD88-dependent signaling prolongs survival and reduces bacterial burden during pulmonary infection with virulent Francisella tularensis.The use of resazurin as a novel antimicrobial agent against Francisella tularensis.Interleukin-12 and interleukin-27 regulate macrophage control of Mycobacterium tuberculosis.Global transcriptional response to spermine, a component of the intramacrophage environment, reveals regulation of Francisella gene expression through insertion sequence elements.Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence.Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium.The presence of interleukin-27 during monocyte-derived dendritic cell differentiation promotes improved antigen processing and stimulation of T cells.IL-12 and IL-27 regulate the phagolysosomal pathway in mycobacteria-infected human macrophages.Elevated interleukin-27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT-1 and STAT-3-dependent manner.Complement C3 as a Prompt for Human Macrophage Death during Infection with Francisella tularensis Strain SCHU S4.The contribution of the glycine cleavage system to the pathogenesis of Francisella tularensis.Interferon-γ, tumor necrosis factor, and interleukin-18 cooperate to control growth of Mycobacterium tuberculosis in human macrophages.Subversion of complement activation at the bacterial surface promotes serum resistance and opsonophagocytosis of Francisella tularensis.Alternative sigma factor RpoN and its modulation protein YhbH are indispensable for Erwinia amylovora virulence.
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Modulation of virulence factors in Francisella tularensis determines human macrophage responses.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 15 February 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Modulation of virulence factor ...... es human macrophage responses.
@en
Modulation of virulence factor ...... es human macrophage responses.
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type
label
Modulation of virulence factor ...... es human macrophage responses.
@en
Modulation of virulence factor ...... es human macrophage responses.
@nl
prefLabel
Modulation of virulence factor ...... es human macrophage responses.
@en
Modulation of virulence factor ...... es human macrophage responses.
@nl
P2093
P2860
P1476
Modulation of virulence factor ...... nes human macrophage responses
@en
P2093
Dawn M O'Dee
James A Carroll
Paul E Carlson
P2860
P304
P356
10.1016/J.MICPATH.2007.02.001
P577
2007-02-15T00:00:00Z