D-512 and D-440 as novel multifunctional dopamine agonists: characterization of neuroprotection properties and evaluation of in vivo efficacy in a Parkinson's disease animal model

D-512 and D-440 as novel multifunctional dopamine agonists: characterization of neuroprotection properties and evaluation of in vivo efficacy in a Parkinson's disease animal model

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http://www.wikidata.org/entity/Q37235660
The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative StressThe high-affinity D2/D3 agonist D512 protects PC12 cells from 6-OHDA-induced apoptotic cell death and rescues dopaminergic neurons in the MPTP mouse model of Parkinson's diseaseMultifunctional D2/D3 agonist D-520 with high in vivo efficacy: modulator of toxicity of alpha-synuclein aggregatesStructural modifications of neuroprotective anti-Parkinsonian (-)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (D-264): an effort toward the improvement of in vivo efficacy of the parent molAdvances and challenges in the search for D2 and D3 dopamine receptor-selective compounds.D-512, a novel dopamine D2/3 receptor agonist, demonstrates greater anti-Parkinsonian efficacy than ropinirole in Parkinsonian rats.Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.Assessment of Protective Role of Multifunctional Dopamine Agonist D-512 Against Oxidative Stress Produced by Depletion of Glutathione in PC12 Cells: Implication in Neuroprotective Therapy for Parkinson's Disease.A novel iron (II) preferring dopamine agonist chelator D-607 significantly suppresses α-syn- and MPTP-induced toxicities in vivo.
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D-512 and D-440 as novel multifunctional dopamine agonists: characterization of neuroprotection properties and evaluation of in vivo efficacy in a Parkinson's disease animal model

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http://www.wikidata.org/entity/Q37235660
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 20 August 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
D-512 and D-440 as novel multi ...... rkinson's disease animal model
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D-512 and D-440 as novel multi ...... kinson's disease animal model.
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type
label
D-512 and D-440 as novel multi ...... rkinson's disease animal model
@en
D-512 and D-440 as novel multi ...... kinson's disease animal model.
@nl
prefLabel
D-512 and D-440 as novel multi ...... rkinson's disease animal model
@en
D-512 and D-440 as novel multi ...... kinson's disease animal model.
@nl
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P1476
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P1433
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D-512 and D-440 as novel multi ...... rkinson's disease animal model
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921
P932