Differential regulation of receptor activation and agonist selectivity by highly conserved tryptophans in the nicotinic acetylcholine receptor binding site.
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Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALEDPrinciples of agonist recognition in Cys-loop receptorsThe binding orientation of epibatidine at α7 nACh receptorsMolecular determinants for competitive inhibition of alpha4beta2 nicotinic acetylcholine receptors.Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeperMerging old and new perspectives on nicotinic acetylcholine receptorsRescue of amyloid-Beta-induced inhibition of nicotinic acetylcholine receptors by a peptide homologous to the nicotine binding domain of the alpha 7 subtype.Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor.Critical Molecular Determinants of α7 Nicotinic Acetylcholine Receptor Allosteric Activation: SEPARATION OF DIRECT ALLOSTERIC ACTIVATION AND POSITIVE ALLOSTERIC MODULATION.Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines.Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors.The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.Persistent activation of α7 nicotinic ACh receptors associated with stable induction of different desensitized states.
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P2860
Differential regulation of receptor activation and agonist selectivity by highly conserved tryptophans in the nicotinic acetylcholine receptor binding site.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Differential regulation of rec ...... choline receptor binding site.
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Differential regulation of rec ...... choline receptor binding site.
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type
label
Differential regulation of rec ...... choline receptor binding site.
@en
Differential regulation of rec ...... choline receptor binding site.
@nl
prefLabel
Differential regulation of rec ...... choline receptor binding site.
@en
Differential regulation of rec ...... choline receptor binding site.
@nl
P2093
P2860
P356
P1476
Differential regulation of rec ...... choline receptor binding site.
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P2093
Clare Stokes
Dustin K Williams
Nicole A Horenstein
Roger L Papke
P2860
P356
10.1124/JPET.109.151225
P407
P577
2009-04-01T00:00:00Z