Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity. - Wikidata - awgldk - TriplyDB

Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity.

Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity.

http://www.wikidata.org/entity/Q37239051

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Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure TCR Signaling in T Cell Memory TNF biology, pathogenic mechanisms and emerging therapeutic strategies NF-κB, the first quarter-century: remarkable progress and outstanding questions NF-κB regulation: lessons from structures Roles of spatial parameters on the oscillation of nuclear NF-κB: computer simulations of a 3D spherical cell Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription Lessons from mathematically modeling the NF-κB pathway.A Regulated, Ubiquitin-Independent Degron in IκBα Ancestral genes can control the ability of horizontally acquired loci to confer new traits Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways B-cell CLL/lymphoma 10 (BCL10) is required for NF-kappaB production by both canonical and noncanonical pathways and for NF-kappaB-inducing kinase (NIK) phosphorylation.The regulatory logic of the NF-kappaB signaling system.IL-17A mediates a selective gene expression profile in asthmatic human airway smooth muscle cells.A genetic algorithm-based Boolean delay model of intracellular signal transduction in inflammation.Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor.The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes.Classical NF-kappaB activation negatively regulates noncanonical NF-kappaB-dependent CXCL12 expression.p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation.A protein turnover signaling motif controls the stimulus-sensitivity of stress response pathways FlowMax: A Computational Tool for Maximum Likelihood Deconvolution of CFSE Time Courses.In vitro γ-ray-induced inflammatory response is dominated by culturing conditions rather than radiation exposures IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer.Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection.Regulation of NF-κB Oscillation by Nuclear Transport: Mechanisms Determining the Persistency and Frequency of Oscillation Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.Statistical Techniques Complement UML When Developing Domain Models of Complex Dynamical Biosystems.Interrogation of inhibitor of nuclear factor κB α/nuclear factor κB (IκBα/NF-κB) negative feedback loop dynamics: from single cells to live animals in vivo.Systems biology approaches to toll-like receptor signaling.NF-κB oscillations translate into functionally related patterns of gene expression.A pathway switch directs BAFF signaling to distinct NFκB transcription factors in maturing and proliferating B cells.Systems biology approaches to dissect mammalian innate immunity Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways A structural guide to proteins of the NF-kappaB signaling module.Late-phase synthesis of IκBα insulates the TLR4-activated canonical NF-κB pathway from noncanonical NF-κB signaling in macrophages.NF-kappaB signaling: multiple angles to target OA.A single NFκB system for both canonical and non-canonical signaling.Consequences of fuzziness in the NFκB/IκBα interaction.NF-κB function in B lymphocytes.

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Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity.

http://www.wikidata.org/entity/Q37239051

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on June 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Kinetic control of negative fe ...... eceptor signaling specificity.

@en

Kinetic control of negative fe ...... eceptor signaling specificity.

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type

label

Kinetic control of negative fe ...... eceptor signaling specificity.

@en

Kinetic control of negative fe ...... eceptor signaling specificity.

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prefLabel

Kinetic control of negative fe ...... eceptor signaling specificity.

@en

Kinetic control of negative fe ...... eceptor signaling specificity.

@nl

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PNAS.0812367106

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Proceedings of the National Academy of Sciences of the United States of America

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Kinetic control of negative fe ...... eceptor signaling specificity.

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Alexander Hoffmann

http://www.w3.org/2001/XMLSchema#string

Gourisankar Ghosh

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Jeffrey D Kearns

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Olga V Savinova

http://www.w3.org/2001/XMLSchema#string

Vincent F-S Shih

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P2860

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

Generation and activation of multiple dimeric transcription factors within the NF-kappaB signaling system

A fourth IkappaB protein within the NF-kappaB signaling module

Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL

From molecular to modular cell biology

Nuclear factor-kappaB in cancer development and progression

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes.

Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism

Circuitry of nuclear factor kappaB signaling.

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9619-9624

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scholarly article

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10.1073/PNAS.0812367106

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24

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106

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2009-06-01T00:00:00Z

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26258433

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19487661

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2701028

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