De novo induction of genetically engineered brain tumors in mice using plasmid DNA
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Engineered Swine Models of CancerGene therapy for brain tumors: basic developments and clinical implementationMouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studiesLipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.Murine cytomegalovirus infection of neural stem cells alters neurogenesis in the developing brainIntegration of epidemiology, immunobiology, and translational research for brain tumorsContribution of tumor heterogeneity in a new animal model of CNS tumors.piggyBac transposon-mediated long-term gene expression in mice.Uncertainty in the translation of preclinical experiments to clinical trials. Why do most phase III clinical trials fail?Gene therapy for brain cancer: combination therapies provide enhanced efficacy and safety.Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression LevelPalbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma.Role of type 1 IFNs in antiglioma immunosurveillance--using mouse studies to guide examination of novel prognostic markers in humans.Somatic genetics empowers the mouse for modeling and interrogating developmental and disease processes.Lentiviral-induced high-grade gliomas in rats: the effects of PDGFB, HRAS-G12V, AKT, and IDH1-R132H.Mechanisms of glioma formation: iterative perivascular glioma growth and invasion leads to tumor progression, VEGF-independent vascularization, and resistance to antiangiogenic therapy.Unexpectedly high copy number of random integration but low frequency of persistent expression of the Sleeping Beauty transposase after trans delivery in primary human T cells.Polygenic in vivo validation of cancer mutations using transposons.Combination of an agonistic anti-CD40 monoclonal antibody and the COX-2 inhibitor celecoxib induces anti-glioma effects by promotion of type-1 immunity in myeloid cells and T-cells.Investigation of oncogenic cooperation in simple liver-specific transgenic mouse models using noninvasive in vivo imaging.COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells.Cancer gene discovery in mouse and man.Transposon mediated integration of plasmid DNA into the subventricular zone of neonatal mice to generate novel models of glioblastoma.Victory and defeat in the induction of a therapeutic response through vaccine therapy for human and canine brain tumors: a review of the state of the art.Differentiation of Glioma Stem Cells and Progenitor Cells into Local Host Cell-Like Cells: A Study Based on Choroidcarcinoma Differentiation of Choroid Plexus of GFP Transgenic Nude Mouse.Review: insights gained from modelling high-grade glioma in the mouse.Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background.Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear CellsReview: In vivo models for defining molecular subtypes of the primitive neuroectodermal tumor genome: current challenges and solutions.Profound impairment of adaptive immune responses by alkylating chemotherapyBlood outgrowth endothelial cell-based systemic delivery of antiangiogenic gene therapy for solid tumors.New approaches for modelling sporadic genetic disease in the mouseImmunogenicity of murine solid tumor models as a defining feature of in vivo behavior and response to immunotherapyATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma.Gene therapy and virotherapy: novel therapeutic approaches for brain tumors.Animal models for glioma drug discovery.What underlies the diversity of brain tumors?Improving drug delivery to primary and metastatic brain tumors: strategies to overcome the blood-brain barrier.Overview of Transgenic Glioblastoma and Oligoastrocytoma CNS Models and Their Utility in Drug Discovery
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P2860
De novo induction of genetically engineered brain tumors in mice using plasmid DNA
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
De novo induction of genetically engineered brain tumors in mice using plasmid DNA
@en
De novo induction of genetically engineered brain tumors in mice using plasmid DNA.
@nl
type
label
De novo induction of genetically engineered brain tumors in mice using plasmid DNA
@en
De novo induction of genetically engineered brain tumors in mice using plasmid DNA.
@nl
prefLabel
De novo induction of genetically engineered brain tumors in mice using plasmid DNA
@en
De novo induction of genetically engineered brain tumors in mice using plasmid DNA.
@nl
P2093
P2860
P1433
P1476
De novo induction of genetically engineered brain tumors in mice using plasmid DNA
@en
P2093
Chunmei Long
Colleen Forster
David A Largaespada
Edward A Zamora
John R Ohlfest
Jon D Larson
Jose L Gallardo
Karen SantaCruz
Katya Ericson
Stacy A Decker
P2860
P304
P356
10.1158/0008-5472.CAN-08-1800
P407
P577
2009-01-01T00:00:00Z