Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity
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Targeting DNA Replication Stress for Cancer Therapyp38MAPK and Chemotherapy: We Always Need to Hear Both Sides of the StoryRho GTPases: Novel Players in the Regulation of the DNA Damage Response?Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBN(p70) protein undergo p38/MK2-dependent premature senescence.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress.Cell cycle profiling by image and flow cytometry: The optimised protocol for the detection of replicational activity using 5-Bromo-2'-deoxyuridine, low concentration of hydrochloric acid and exonuclease III.Pivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases.RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy.Revisiting p53 for cancer-specific chemo- and radiotherapy: ten years after.Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitorsAntitumor mechanisms when pRb and p53 are genetically inactivated.The MAPK-activated protein kinase 2 mediates gemcitabine sensitivity in pancreatic cancer cells.Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells.A bright quantum of time in the Cleaver Laboratory; a tribute and retrospective.CDKN2A/p16 deletion in head and neck cancer cells is associated with Cdk2 activation, replication stress, and vulnerability to Chk1 inhibition.Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.
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Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 30 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Damage-induced DNA replication ...... ated protein kinase 2 activity
@en
Damage-induced DNA replication ...... ted protein kinase 2 activity.
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type
label
Damage-induced DNA replication ...... ated protein kinase 2 activity
@en
Damage-induced DNA replication ...... ted protein kinase 2 activity.
@nl
prefLabel
Damage-induced DNA replication ...... ated protein kinase 2 activity
@en
Damage-induced DNA replication ...... ted protein kinase 2 activity.
@nl
P2093
P2860
P50
P356
P1476
Damage-induced DNA replication ...... ated protein kinase 2 activity
@en
P2093
Cathrin Bierwirth
Claus Storgaard Sørensen
Dominique Kranz
Frederik Köpper
Ingegerd Elvers
Margarete Schön
Meike Kunze
Priyanka Saini
P2860
P304
16856-16861
P356
10.1073/PNAS.1304355110
P407
P577
2013-09-30T00:00:00Z