about
UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heartMDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53p73 and p63: why do we still need them?NF-Y dependent epigenetic modifications discriminate between proliferating and postmitotic tissue.HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancerp53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrestNucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.A polymorphic microsatellite that mediates induction of PIG3 by p53.E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis.Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulation.Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice.While p73 is essential, p63 is completely dispensable for the development of the central nervous system5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair.p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis.Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.In vitro selection of RNA ligands for the ribosomal L22 protein associated with Epstein-Barr virus-expressed RNA by using randomized and cDNA-derived RNA librariesImproving survival by exploiting tumour dependence on stabilized mutant p53 for treatmentProtection against apoptosis by the vaccinia virus SPI-2 (B13R) gene productExport of hepatitis B virus RNA on a Rev-like pathway: inhibition by the regenerating liver inhibitory factor IkappaB alpha.Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress.The MDM2 oncoprotein binds specifically to RNA through its RING finger domainUsp22 deficiency impairs intestinal epithelial lineage specification in vivoDamage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activityThe alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteinsTAp73 is essential for germ cell adhesion and maturation in testis.Targeting tumour-supportive cellular machineries in anticancer drug development.Mdm2 inhibition confers protection of p53-proficient cells from the cytotoxic effects of Wee1 inhibitorsE1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53.Inactivation of p53 but not p73 by adenovirus type 5 E1B 55-kilodalton and E4 34-kilodalton oncoproteins.DeltaNp73 can modulate the expression of various genes in a p53-independent fashion.Exploiting replicative stress to treat cancer.The MAPK-activated protein kinase 2 mediates gemcitabine sensitivity in pancreatic cancer cells.MicroRNA-101 Suppresses Tumor Cell Proliferation by Acting as an Endogenous Proteasome Inhibitor via Targeting the Proteasome Assembly Factor POMP.Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death.Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells.Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g.Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein.The nuclear export signal within the E4orf6 protein of adenovirus type 5 supports virus replication and cytoplasmic accumulation of viral mRNA.Viral and cellular factors that target the promyelocytic leukemia oncogenic domains strongly activate a glucocorticoid-responsive promoter
P50
Q27853065-DC939E2D-5BD3-442F-8855-076287A32FADQ28244342-650B6259-15EF-4BA9-8926-BA9AFF349EDFQ28271894-CABC088F-3762-4D92-BB18-AA83BCB071D8Q28611382-F2FE0E0E-2632-4F63-983D-B711584EB755Q33330321-A842655F-00D0-4450-BA5C-45AE68D63AAAQ33694931-5761D159-4E11-4013-BCEE-8A649C5544BEQ33719450-998DC751-34A8-4536-9C01-719DCE9338A7Q33888123-A9F0B91D-87CC-4677-A20B-F7504F75FC02Q34120918-AAB53148-32C4-43B8-A0CB-80B09362EFF2Q35015916-643B6BC1-B95A-4A6F-B31F-953CD3DD9383Q35067924-A54F8EB4-0800-4C93-92D2-172852FC0706Q35135731-B7F0874C-175A-4A97-95F4-AD1675B51721Q35215447-F43101E2-60B4-4F30-B9B3-7280229F674FQ35613493-A127EECB-5BD7-4429-BDBD-E832825460E7Q35679611-6416BDE5-B979-44DF-B58F-7D04EEEDA981Q35760817-3F5CCB53-6945-4412-9C3C-13CAFEA10F1AQ35852608-2971FA19-9F20-4313-B1EC-70526BCBD7B0Q35862613-2CAEFA7B-9504-4462-A9F2-784277D31F58Q35869096-9DFFD9EB-6F3D-4CC7-99E5-65E0542098CFQ35899426-1389C7A3-D8AE-47B4-BF2B-CEADC9B0FC05Q35955216-0EA88E80-FE45-476A-AF8F-0522CB08877EQ36437940-3ECDB76F-3564-405C-A416-B2DD0E6441A9Q36545916-57E36AF9-A067-42BF-AECA-64B8176FE1B1Q37240588-5293A596-7001-4DD8-8532-0C2A30D489C1Q37423576-C800121C-E2CB-4864-86DB-CDAD2A2215BBQ37677588-65124139-99E3-4B22-8899-64084B0641FEQ38191794-CDF1D4AB-EEC0-404F-AFCA-FF2FF0303594Q38261022-3EA621A5-A909-45FA-BD92-41ACD374848AQ38317803-2C0AB7FB-22D8-49C2-B1BB-6F6328ECC465Q38332683-AA87BD9D-E75B-4BA1-93CD-49CA9F64C785Q38348098-8AE8BA4F-4BE5-4FD7-95A9-DF5D900399C6Q38466329-75DDF9AA-FDC0-4486-AF87-335EBAE9387AQ38717784-83540F8E-C387-431A-BFC7-FC3BEBD80342Q38856491-597CF522-83CF-4939-91C0-E203AB39EB79Q38869610-AC125187-8C13-42DD-B282-9ED61DE35C18Q38919423-21880C3D-FA9C-4970-8877-C59749C97368Q39112884-3AFCCF16-3AFB-4172-B9A0-D73399B2BE61Q39551896-F22D45D1-AA02-465B-BDE2-D04B8AD45E5CQ39588948-3B363B12-D681-4053-A2BB-621BD4581CEDQ39606266-FF085A5B-6B8F-4E99-9437-FE23E068B9FB
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Matthias Dobbelstein
@ast
Matthias Dobbelstein
@en
Matthias Dobbelstein
@es
Matthias Dobbelstein
@nl
Matthias Dobbelstein
@sl
type
label
Matthias Dobbelstein
@ast
Matthias Dobbelstein
@en
Matthias Dobbelstein
@es
Matthias Dobbelstein
@nl
Matthias Dobbelstein
@sl
prefLabel
Matthias Dobbelstein
@ast
Matthias Dobbelstein
@en
Matthias Dobbelstein
@es
Matthias Dobbelstein
@nl
Matthias Dobbelstein
@sl
P106
P21
P31
P496
0000-0001-5052-3967