Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis.
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The genome of the kinetoplastid parasite, Leishmania majorAcidocalcisomesNew insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protistsLeishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesisSterol biosynthesis is required for heat resistance but not extracellular survival in leishmaniaTranscriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular InfectionDe novo sphingolipid synthesis is essential for viability, but not for transport of glycosylphosphatidylinositol-anchored proteins, in African trypanosomes.Developmentally regulated sphingolipid degradation in Leishmania majorDegradation of host sphingomyelin is essential for Leishmania virulence.The role of acidocalcisomes in parasitic protists.Phospholipid and sphingolipid metabolism in Leishmania.Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbesDETC induces Leishmania parasite killing in human in vitro and murine in vivo models: a promising therapeutic alternative in Leishmaniasis.Cell-free synthesis and functional characterization of sphingolipid synthases from parasitic trypanosomatid protozoa.Expansion of the target of rapamycin (TOR) kinase family and function in Leishmania shows that TOR3 is required for acidocalcisome biogenesis and animal infectivity.Metabolic variation during development in culture of Leishmania donovani promastigotes.Sphingolipids in parasitic protozoaThe role of the mitochondrial glycine cleavage complex in the metabolism and virulence of the protozoan parasite Leishmania majorRole of sphingolipids in microbial pathogenesisModulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites.Adaptor protein-3 (AP-3) complex mediates the biogenesis of acidocalcisomes and is essential for growth and virulence of Trypanosoma brucei.Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania.Sphingolipid and ceramide homeostasis: potential therapeutic targets.Comparisons of mutants lacking the Golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania majorThe role of acidocalcisomes in the stress response of Trypanosoma cruzi.Inositolphosphoceramide metabolism in Trypanosoma cruzi as compared with other trypanosomatids.Leishmania parasites possess a platelet-activating factor acetylhydrolase important for virulence.Phospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi.The amastigote forms of Leishmania are experts at exploiting host cell processes to establish infection and persist.Developmentally regulated sphingolipid synthesis in African trypanosomesPlasmenylethanolamine synthesis in Leishmania major.Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexansSterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs.Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence.The potential of mass spectrometry for the global profiling of parasite metabolomes.Central carbon metabolism of Leishmania parasites.Targeting of the hydrophobic metabolome by pathogens.Endocytosis and Sphingolipid Scavenging in Leishmania mexicana Amastigotes.Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis.Characterization of inositol phosphorylceramides from Leishmania major by tandem mass spectrometry with electrospray ionization.
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P2860
Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2005
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Leishmania salvage and remodel ...... and acidocalcisome biogenesis.
@en
Leishmania salvage and remodel ...... and acidocalcisome biogenesis.
@nl
type
label
Leishmania salvage and remodel ...... and acidocalcisome biogenesis.
@en
Leishmania salvage and remodel ...... and acidocalcisome biogenesis.
@nl
prefLabel
Leishmania salvage and remodel ...... and acidocalcisome biogenesis.
@en
Leishmania salvage and remodel ...... and acidocalcisome biogenesis.
@nl
P2093
P2860
P1476
Leishmania salvage and remodel ...... and acidocalcisome biogenesis.
@en
P2093
David A Scott
Fong-Fu Hsu
Roberto Docampo
P2860
P304
P356
10.1111/J.1365-2958.2005.04493.X
P407
P577
2005-03-01T00:00:00Z