Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B.
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Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay.Pharmacokinetic/Pharmacodynamic Modeling of the PDE4 Inhibitor TAK-648 in Type 2 Diabetes: Early Translational Approaches for Human Dose PredictionMice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosisAdvances in targeting cyclic nucleotide phosphodiesterasesCyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.Synergistic effects of polyphenols and methylxanthines with Leucine on AMPK/Sirtuin-mediated metabolism in muscle cells and adipocytesAdenylyl Cyclase Type 5 Deficiency Protects Against Diet-Induced Obesity and Insulin ResistanceAlterations in cyclic nucleotide phosphodiesterase activities in omental and subcutaneous adipose tissues in human obesity.Resveratrol as a calorie restriction mimetic: therapeutic implications.Metabolic benefits of inhibiting cAMP-PDEs with resveratrol.Apremilast: A Phosphodiesterase 4 Inhibitor for the Treatment of Psoriatic Arthritis.Metabolic effects of resveratrol: addressing the controversies.Phosphodiesterase-4 inhibition as a therapeutic strategy for metabolic disorders.AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.Insulin immuno-neutralization in fed chickens: effects on liver and muscle transcriptome.Diet-induced obesity and insulin resistance are associated with brown fat degeneration in SIRT1-deficient mice.Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism.Hypothalamic Phosphodiesterase 3B Pathway Mediates Anorectic and Body Weight-Reducing Effects of Insulin in Male Mice.Phosphodiesterase-4B as a Therapeutic Target for Cognitive Impairment and Obesity-Related Metabolic Diseases.The effects of forskolin and rolipram on cAMP, cGMP and free fatty acid levels in diet induced obesity.Update on the treatment of psoriasis and psoriatic arthritis - role of apremilast.
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Reduced adiposity and high-fat diet-induced adipose inflammation in mice deficient for phosphodiesterase 4B.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Reduced adiposity and high-fat ...... ient for phosphodiesterase 4B.
@en
Reduced adiposity and high-fat ...... ient for phosphodiesterase 4B.
@nl
type
label
Reduced adiposity and high-fat ...... ient for phosphodiesterase 4B.
@en
Reduced adiposity and high-fat ...... ient for phosphodiesterase 4B.
@nl
prefLabel
Reduced adiposity and high-fat ...... ient for phosphodiesterase 4B.
@en
Reduced adiposity and high-fat ...... ient for phosphodiesterase 4B.
@nl
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Reduced adiposity and high-fat ...... ient for phosphodiesterase 4B.
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Jeffrey S Flier
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P304
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10.1210/EN.2009-0108
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P577
2009-04-09T00:00:00Z