Sequestration of E12/E47 and suppression of p27KIP1 play a role in Id2-induced proliferation and tumorigenesis

Sequestration of E12/E47 and suppression of p27KIP1 play a role in Id2-induced proliferation and tumorigenesis

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http://www.wikidata.org/entity/Q37246688
Inorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patternsId2, Id3 and Id4 overcome a Smad7-mediated block in tumorigenesis, generating TGF-β-independent melanoma.Smad7 restricts melanoma invasion by restoring N-cadherin expression and establishing heterotypic cell-cell interactions in vivo.Id3 induces an Elk-1-caspase-8-dependent apoptotic pathway in squamous carcinoma cellsRP58 controls neuron and astrocyte differentiation by downregulating the expression of Id1-4 genes in the developing cortex.The function of p27 KIP1 during tumor development.Downregulation of Id2 increases chemosensitivity of glioma.p27(kip1) upregulated by hnRNPC1/2 antagonizes CagA (a virulence factor of Helicobacter pylori)-mediated pathogenesis.Inhibitor of differentiation-4 (Id4) stimulates pigmentation in melanoma leading to histiocyte infiltration.Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis.E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53.
P2860

Sequestration of E12/E47 and suppression of p27KIP1 play a role in Id2-induced proliferation and tumorigenesis

Item
http://www.wikidata.org/entity/Q37246688
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Sequestration of E12/E47 and s ...... roliferation and tumorigenesis
@en
Sequestration of E12/E47 and s ...... oliferation and tumorigenesis.
@nl
type
label
Sequestration of E12/E47 and s ...... roliferation and tumorigenesis
@en
Sequestration of E12/E47 and s ...... oliferation and tumorigenesis.
@nl
prefLabel
Sequestration of E12/E47 and s ...... roliferation and tumorigenesis
@en
Sequestration of E12/E47 and s ...... oliferation and tumorigenesis.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Sequestration of E12/E47 and s ...... roliferation and tumorigenesis
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932