The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth.
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Non-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesisWillin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylationCrumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein ExpandedThe NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signalingNf2/Merlin controls progenitor homeostasis and tumorigenesis in the liverThe apical-basal cell polarity determinant Crumbs regulates Hippo signaling in DrosophilaSu(dx) E3 ubiquitin ligase-dependent and -independent functions of polychaetoid, the Drosophila ZO-1 homologueHippo signaling: growth control and beyond.Dying cells protect survivors from radiation-induced cell death in Drosophila.Loss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis.Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.Drosophila GAGA factor is required for full activation of the dE2f1-Yki/Sd transcriptional program.The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy.Rottlerin exhibits antitumor activity via down-regulation of TAZ in non-small cell lung cancer.Yorkie: the final destination of Hippo signaling.Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathwayMammalian Hippo pathway: from development to cancer and beyond.The Hippo pathway and apico-basal cell polarity.Integration of intercellular signaling through the Hippo pathwayPolarizing pathways: balancing endothelial polarity, permeability, and lumen formation.Binary regulation of Hippo pathway by Merlin/NF2, Kibra, Lgl, and Melted specifies and maintains postmitotic neuronal fate.Cell-cell junctions: α-catenin and E-cadherin help fence in Yap1.Regulation of cytoskeletal organization and junctional remodeling by the atypical cadherin Fat.Signal integration in TGF-β, WNT, and Hippo pathwaysA screen for conditional growth suppressor genes identifies the Drosophila homolog of HD-PTP as a regulator of the oncoprotein Yorkie.Polycystin-2 activity is controlled by transcriptional coactivator with PDZ binding motif and PALS1-associated tight junction protein.Differences in levels of the transmembrane protein Crumbs can influence cell survival at clonal boundaries.Atypical cadherins Dachsous and Fat control dynamics of noncentrosomal microtubules in planar cell polarity.Fosmid-based structure-function analysis reveals functionally distinct domains in the cytoplasmic domain of Drosophila crumbs.Essential role of the ERK/MAPK pathway in blood-placental barrier formation.Crumbs, Moesin and Yurt regulate junctional stability and dynamics for a proper morphogenesis of the Drosophila pupal wing epithelium.Mechanical strain regulates the Hippo pathway in Drosophila.Yorkie Regulates Neurodegeneration Through Canonical Pathway and Innate Immune Response.Fat/Hippo pathway regulates the progress of neural differentiation signaling in the Drosophila optic lobe.Hippo-yap signaling in ocular development and disease.Regulation of cell proliferation and adhesion by means of a novel region of drosophila merlin interacting with Sip1.A Drosophila Tumor Suppressor Gene Prevents Tonic TNF Signaling through Receptor N-Glycosylation.
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The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Hippo tumor-suppressor pat ...... in parallel to tissue growth.
@en
The Hippo tumor-suppressor pat ...... in parallel to tissue growth.
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type
label
The Hippo tumor-suppressor pat ...... in parallel to tissue growth.
@en
The Hippo tumor-suppressor pat ...... in parallel to tissue growth.
@nl
prefLabel
The Hippo tumor-suppressor pat ...... in parallel to tissue growth.
@en
The Hippo tumor-suppressor pat ...... in parallel to tissue growth.
@nl
P2093
P2860
P356
P1476
The Hippo tumor-suppressor pat ...... in parallel to tissue growth.
@en
P2093
Chunyao Tao
Clayton Morrison
Fisun Hamaratoglu
Georg Halder
Kathleen Gajewski
Leticia Sansores-Garcia
P2860
P304
P356
10.1242/JCS.046482
P407
P577
2009-06-16T00:00:00Z