Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys
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Fetal programming of polycystic ovary syndromeNonhuman primate models of polycystic ovary syndromePioglitazone increases whole body insulin sensitivity in obese, insulin-resistant rhesus monkeysThe Effects of a Single Developmentally Entrained Pulse of Testosterone in Female Neonatal Mice on Reproductive and Metabolic Functions in Adult Life.Prenatal androgenization of female mice programs an increase in firing activity of gonadotropin-releasing hormone (GnRH) neurons that is reversed by metformin treatment in adulthoodEffects of prenatal androgens on rhesus monkeys: a model system to explore the organizational hypothesis in primates.Developmental programming: impact of prenatal testosterone excess and postnatal weight gain on insulin sensitivity index and transfer of traits to offspring of overweight femalesImpaired preadipocyte differentiation into adipocytes in subcutaneous abdominal adipose of PCOS-like female rhesus monkeysFetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys.Polycystic ovary syndrome and its developmental origins.Developmental programming: insulin sensitizer treatment improves reproductive function in prenatal testosterone-treated female sheepAbnormal infant islet morphology precedes insulin resistance in PCOS-like monkeysExperimentally induced gestational androgen excess disrupts glucoregulation in rhesus monkey dams and their female offspring.Early-to-mid gestation fetal testosterone increases right hand 2D:4D finger length ratio in polycystic ovary syndrome-like monkeys.PPARG regulates gonadotropin-releasing hormone signaling in LbetaT2 cells in vitro and pituitary gonadotroph function in vivo in mice.Fetal programming of adrenal androgen excess: lessons from a nonhuman primate model of polycystic ovary syndrome.Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys.Developmental origin of reproductive and metabolic dysfunctions: androgenic versus estrogenic reprogramming.Nonhuman primates as models for human adrenal androgen production: function and dysfunction.Effect of maternal PCOS and PCOS-like phenotype on the offspring's health.Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits.Pharmacokinetics of pioglitazone after multiple oral dose administration in horses.World Congress on the Insulin Resistance Syndrome, 2009: Insulin resistance mechanisms, the brain, and insulin resistance in youth and in the polycystic ovary syndrome.Sex Differences in Androgen Regulation of Metabolism in Nonhuman Primates.Mechanistic links between oxidative/nitrosative stress and tumor necrosis factor alpha in letrozole-induced murine polycystic ovary: biochemical and pathological evidences for beneficial effect of pioglitazone.Ovarian and Extra-Ovarian Mediators in the Development of Polycystic Ovary Syndrome
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P2860
Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 January 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Pioglitazone improves insulin ...... ogenized female rhesus monkeys
@en
Pioglitazone improves insulin ...... genized female rhesus monkeys.
@nl
type
label
Pioglitazone improves insulin ...... ogenized female rhesus monkeys
@en
Pioglitazone improves insulin ...... genized female rhesus monkeys.
@nl
prefLabel
Pioglitazone improves insulin ...... ogenized female rhesus monkeys
@en
Pioglitazone improves insulin ...... genized female rhesus monkeys.
@nl
P2093
P2860
P1476
Pioglitazone improves insulin ...... ogenized female rhesus monkeys
@en
P2093
Cristin M Bruns
Daniel A Dumesic
David H Abbott
Ian M Bird
Joseph W Kemnitz
Theodore L Goodfriend
P2860
P304
P356
10.1016/J.REPROTOX.2006.12.009
P577
2007-01-14T00:00:00Z