Tandemly Integrated HPV16 Can Form a Brd4-Dependent Super-Enhancer-Like Element That Drives Transcription of Viral Oncogenes
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The role of integration in oncogenic progression of HPV-associated cancersNasopharyngeal carcinoma super-enhancer-driven ETV6 correlates with prognosis.Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer.Immune disease-associated variants in gene enhancers point to BET epigenetic mechanisms for therapeutic intervention.Super-Enhancer-Driven Transcriptional Dependencies in Cancer.Oncogenic human papillomaviruses.Regulation of the human papillomavirus type 16 late promoter by transcriptional elongation.Sp100 colocalizes with HPV replication foci and restricts the productive stage of the infectious cycleIntegrated analysis of whole-genome ChIP-Seq and RNA-Seq data of primary head and neck tumor samples associates HPV integration sites with open chromatin marks.Human Papillomavirus Genome Integration and Head and Neck Cancer.HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression.
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Tandemly Integrated HPV16 Can Form a Brd4-Dependent Super-Enhancer-Like Element That Drives Transcription of Viral Oncogenes
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 September 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Tandemly Integrated HPV16 Can ...... anscription of Viral Oncogenes
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Tandemly Integrated HPV16 Can ...... nscription of Viral Oncogenes.
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Tandemly Integrated HPV16 Can ...... anscription of Viral Oncogenes
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Tandemly Integrated HPV16 Can ...... nscription of Viral Oncogenes.
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Tandemly Integrated HPV16 Can ...... anscription of Viral Oncogenes
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Tandemly Integrated HPV16 Can ...... nscription of Viral Oncogenes.
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Tandemly Integrated HPV16 Can ...... anscription of Viral Oncogenes
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Alison A McBride
Alix Warburton
Katharine E Dooley
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10.1128/MBIO.01446-16
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2016-09-13T00:00:00Z