MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.
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Identification of mitogen-activated protein/extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-largeEmerging treatment options to improve cardiovascular outcomes in patients with acute coronary syndrome: focus on losmapimodTitin-based tension in the cardiac sarcomere: molecular origin and physiological adaptationsPrincipal component analysis-based unsupervised feature extraction applied to in silico drug discovery for posttraumatic stress disorder-mediated heart diseaseTargeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signalingScutellarin alleviates interstitial fibrosis and cardiac dysfunction of infarct rats by inhibiting TGFβ1 expression and activation of p38-MAPK and ERK1/2Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overloadInterstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanismMURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by α1-adrenergic receptors.RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix.Small molecule inhibitors targeting activator protein 1 (AP-1).The protective role of 5-hydroxymethyl-2-furfural (5-HMF) against acute hypobaric hypoxiaA concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosisDeep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: an in vitro and in vivo studyExercise and Glycemic Control: Focus on Redox Homeostasis and Redox-Sensitive Protein Signaling.Protein Kinases as Drug Development Targets for Heart Disease TherapyShear stress modulation of smooth muscle cell marker genes in 2-D and 3-D depends on mechanotransduction by heparan sulfate proteoglycans and ERK1/2.Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway.Fistular onion stalk extract exhibits anti-atherosclerotic effects in rats.FGF23 induces left ventricular hypertrophyCalcium channel blockers, more than diuretics, enhance vascular protective effects of angiotensin receptor blockers in salt-loaded hypertensive rats.Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.Thyroid hormone inhibits ERK phosphorylation in pressure overload-induced hypertrophied mouse hearts through a receptor-mediated mechanism.Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signalingBerberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE(-/-) mice.The protective role of 5-HMF against hypoxic injury.Activity of Bradykinin B2 Receptor Is Regulated by Long-Chain Polyunsaturated Fatty Acids.Pipoxolan ameliorates cerebral ischemia via inhibition of neuronal apoptosis and intimal hyperplasia through attenuation of VSMC migration and modulation of matrix metalloproteinase-2/9 and Ras/MEK/ERK signaling pathwaysKlotho suppresses cardiomyocyte apoptosis in mice with stress-induced cardiac injury via downregulation of endoplasmic reticulum stress.Effect of aged bone marrow microenvironment on mesenchymal stem cell migration.Function of CD147 in atherosclerosis and atherothrombosisMicroRNAs involved in the mitogen-activated protein kinase cascades pathway during glucose-induced cardiomyocyte hypertrophy.Smooth muscle specific overexpression of p22phox potentiates carotid artery wall thickening in response to injury.Dihydroaustrasulfone alcohol inhibits PDGF-induced proliferation and migration of human aortic smooth muscle cells through inhibition of the cell cycle.Activator protein-1 (AP-1) signalling in human atherosclerosis: results of a systematic evaluation and intervention studyHuman Engineered Cardiac Tissues Created Using Induced Pluripotent Stem Cells Reveal Functional Characteristics of BRAF-Mediated Hypertrophic Cardiomyopathy.Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in MiceRosuvastatin Attenuates CD40L-Induced Downregulation of Extracellular Matrix Production in Human Aortic Smooth Muscle Cells via TRAF6-JNK-NF-κB Pathway.Influence of long-term caloric restriction on myocardial and cardiomyocyte contractile function and autophagy in mice.
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MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
MAPK signalling in cardiovascu ...... nisms and therapeutic targets.
@en
MAPK signalling in cardiovascu ...... nisms and therapeutic targets.
@nl
type
label
MAPK signalling in cardiovascu ...... nisms and therapeutic targets.
@en
MAPK signalling in cardiovascu ...... nisms and therapeutic targets.
@nl
prefLabel
MAPK signalling in cardiovascu ...... nisms and therapeutic targets.
@en
MAPK signalling in cardiovascu ...... nisms and therapeutic targets.
@nl
P2860
P356
P1433
P1476
MAPK signalling in cardiovascu ...... nisms and therapeutic targets.
@en
P2093
Anthony J Muslin
P2860
P304
P356
10.1042/CS20070430
P407
P577
2008-10-01T00:00:00Z