Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.

Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.

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http://www.wikidata.org/entity/Q37259702
Antileukemia Effect of Ciclopirox Olamine Is Mediated by Downregulation of Intracellular Ferritin and Inhibition β-Catenin-c-Myc Signaling Pathway in Glucocorticoid Resistant T-ALL Cell LinesCiclopirox inhibits cancer cell proliferation by suppression of Cdc25A.Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathwayIn Vitro Antileukemic Activity of Xanthosoma sagittifolium (Taioba) Leaf Extract.Targeting PI3K/AKT/mTOR network for treatment of leukemia.Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK.The synergistic effect of SAHA and parthenolide in MDA-MB231 breast cancer cells.Selective activity of the histone deacetylase inhibitor AR-42 against leukemia stem cells: a novel potential strategy in acute myelogenous leukemia.Protein kinase inhibitors for acute leukemia.Combined analysis of gene expression and genome binding profiles identified potential therapeutic targets of ciclopirox in Ewing sarcoma.Superior efficacy of the antifungal agent ciclopirox olamine over gemcitabine in pancreatic cancer models.Complementary effects of ciclopirox olamine, a prolyl hydroxylase inhibitor and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting.Ciclopirox activates ATR-Chk1 signaling pathway leading to Cdc25A protein degradation.
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Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.

Item
http://www.wikidata.org/entity/Q37259702
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
@en
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
@nl
type
label
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
@en
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
@nl
prefLabel
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
@en
Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.
@nl
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Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity
@en
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P2860
P304
P31
P356
10.1016/J.EXPHEM.2013.04.012
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