ATF6 modulates SREBP2-mediated lipogenesis. - Wikidata - awgldk - TriplyDB

ATF6 modulates SREBP2-mediated lipogenesis.

ATF6 modulates SREBP2-mediated lipogenesis.

http://www.wikidata.org/entity/Q37260315

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Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases Mitochondrial fatty acid oxidation in obesity Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish Activating transcription factor 6 protects insulin receptor from ER stress-stimulated desensitization via p42/44 ERK pathway Sterol Regulatory Element-Binding Proteins (SREBP) signalling High mobility group protein-B1 interacts with sterol regulatory element-binding proteins to enhance their DNA binding.Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78 Genome-wide patterns of promoter sharing and co-expression in bovine skeletal muscle.Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response.The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and Cancer Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells Calcium-independent phospholipase A2γ enhances activation of the ATF6 transcription factor during endoplasmic reticulum stress.Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.Primate-specific evolution of an LDLR enhancer.Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential Beta-Cell Injury in Ncb5or-null Mice is Exacerbated by Consumption of a High-Fat Diet.Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice Amyloid precursor protein controls cholesterol turnover needed for neuronal activity.Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs.Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility.SREBPs: protein interaction and SREBPs.The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease.Unfolded protein response signaling and metabolic diseases.Mild lipid stress induces profound loss of MC4R protein abundance and function.Variation in genes related to hepatic lipid metabolism and changes in waist circumference and body weight.The Golgi apparatus: an organelle with multiple complex functions.The genetics of familial combined hyperlipidaemia.Signaling circuits on the Golgi complex.A pathway approach to investigate the function and regulation of SREBPs.Regulation of Golgi signaling and trafficking by the KDEL receptor.The unfolded protein response in fatty liver disease.Signaling pathways from the endoplasmic reticulum and their roles in disease OSAS-related inflammatory mechanisms of liver injury in nonalcoholic fatty liver disease.Endoplasmic reticulum stress and Oxidative stress in the pathogenesis of Non-alcoholic fatty liver disease.The role of ER stress in lipid metabolism and lipotoxicity.Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA.ER stress and autophagy dysfunction contribute to fatty liver in diabetic mice.

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ATF6 modulates SREBP2-mediated lipogenesis.

http://www.wikidata.org/entity/Q37260315

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 05 February 2004

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

ATF6 modulates SREBP2-mediated lipogenesis.

@en

ATF6 modulates SREBP2-mediated lipogenesis.

@nl

type

label

ATF6 modulates SREBP2-mediated lipogenesis.

@en

ATF6 modulates SREBP2-mediated lipogenesis.

@nl

prefLabel

ATF6 modulates SREBP2-mediated lipogenesis.

@en

ATF6 modulates SREBP2-mediated lipogenesis.

@nl

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SJ.EMBOJ.7600106

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The EMBO Journal

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ATF6 modulates SREBP2-mediated lipogenesis

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John Y-J Shyy

http://www.w3.org/2001/XMLSchema#string

Kazutoshi Mori

http://www.w3.org/2001/XMLSchema#string

Lingfang Zeng

http://www.w3.org/2001/XMLSchema#string

Min Lu

http://www.w3.org/2001/XMLSchema#string

Shengzhan Luo

http://www.w3.org/2001/XMLSchema#string

Yi Zhu

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein

Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response

Dimerization of sterol regulatory element-binding protein 2 via the helix-loop-helix-leucine zipper domain is a prerequisite for its nuclear localization mediated by importin beta

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

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950-958

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scholarly article

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10.1038/SJ.EMBOJ.7600106

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4

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23

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2004-02-05T00:00:00Z

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8884585

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