Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas - Wikidata - awgldk - TriplyDB

Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas

Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas

http://www.wikidata.org/entity/Q37265022

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Aberrant Promoter Hypomethylation in CLL: Does It Matter for Disease Development?Epigenetic impact of infection on carcinogenesis: mechanisms and applications ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex DNMT3A in haematological malignancies.Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis.β-elemene inhibited expression of DNA methyltransferase 1 through activation of ERK1/2 and AMPKα signalling pathways in human lung cancer cells: the role of Sp1.Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells Burkitt lymphoma beyond MYC translocation: N-MYC and DNA methyltransferases dysregulation.Dnmt3a Is a Haploinsufficient Tumor Suppressor in CD8+ Peripheral T Cell Lymphoma.Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.Loss of Dnmt3a induces CLL and PTCL with distinct methylomes and transcriptomes in mice Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK.DNA methyltransferases and their roles in tumorigenesis.Genetic mutations in epigenetic modifiers as therapeutic targets in acute myeloid leukemia.DNA methylation in normal and malignant hematopoiesis.Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity.Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis.DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt's lymphoma.The inhibitory activity of gallic acid against DNA methylation: application of gallic acid on epigenetic therapy of human cancers.USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy

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Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas

http://www.wikidata.org/entity/Q37265022

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 03 September 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Essential role for Dnmt1 in th ...... f MYC-induced T-cell lymphomas

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Essential role for Dnmt1 in th ...... MYC-induced T-cell lymphomas.

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Essential role for Dnmt1 in th ...... f MYC-induced T-cell lymphomas

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Essential role for Dnmt1 in th ...... MYC-induced T-cell lymphomas.

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Essential role for Dnmt1 in th ...... f MYC-induced T-cell lymphomas

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Essential role for Dnmt1 in th ...... MYC-induced T-cell lymphomas.

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Molecular and Cellular Biology

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Essential role for Dnmt1 in th ...... f MYC-induced T-cell lymphomas

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Adam R Karpf

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David Klinkebiel

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Jana Opavska

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Lizhao Wu

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Lynette M Smith

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Melanie A Simpson

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Rene Opavsky

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Robert E Lewis

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Ryan A Hlady

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Slavomira Novakova

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P2860

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Comprehensive molecular characterization of human colon and rectal cancer

DNMT3A Mutations in Acute Myeloid Leukemia

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

The epigenomics of cancer

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4321-4333

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scholarly article

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10.1128/MCB.00776-13

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2013-09-03T00:00:00Z

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24001767

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