Unique hexosaminidase reduces metabolic survival signal and sensitizes cardiac myocytes to hypoxia/reoxygenation injury.
about
Cell-Penetrant, Nanomolar O-GlcNAcase Inhibitors Selective against Lysosomal HexosaminidasesO-GlcNAcylation and oxidation of proteins: is signalling in the cardiovascular system becoming sweeter?Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolismO-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stressThe hexosamine signaling pathway: O-GlcNAc cycling in feast or famineAltering O-linked β-N-acetylglucosamine cycling disrupts mitochondrial function.Responses of hypertrophied myocytes to reactive species: implications for glycolysis and electrophile metabolismO-GlcNAc modification of NFκB p65 inhibits TNF-α-induced inflammatory mediator expression in rat aortic smooth muscle cellsProteasomal degradation of O-GlcNAc transferase elevates hypoxia-induced vascular endothelial inflammatory response†.O-GlcNAc signaling in the cardiovascular system.Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags.Protein O-GlcNAcylation and cardiovascular (patho)physiology.Analysis of high-altitude de-acclimatization syndrome after exposure to high altitudes: a cluster-randomized controlled trialThe protective role of 5-HMF against hypoxic injury.Bioenergetic function in cardiovascular cells: the importance of the reserve capacity and its biological regulationHigh fat feeding in mice is insufficient to induce cardiac dysfunction and does not exacerbate heart failure.High glucose induces mitochondrial dysfunction independently of protein O-GlcNAcylation.O-GlcNAcylation Negatively Regulates Cardiomyogenic Fate in Adult Mouse Cardiac Mesenchymal Stromal Cells.The dynamic stress-induced "O-GlcNAc-ome" highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways.The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease.O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy.Loss of mitofusin 2 promotes endoplasmic reticulum stress.Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependentCytoskeletal keratin glycosylation protects epithelial tissue from injury.Association between Serum Interleukin-17A Level and High-Altitude Deacclimatization Syndrome.Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis.O-linked beta-N-acetylglucosamine during hyperglycemia exerts both anti-inflammatory and pro-oxidative properties in the endothelial systemO-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death.The role of protein O-linked beta-N-acetylglucosamine in mediating cardiac stress responses.Cardiomyocyte Ogt is essential for postnatal viability.O-GlcNAc and the cardiovascular system.Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway.Protein O-linked β-N-acetylglucosamine: a novel effector of cardiomyocyte metabolism and function.Glycosylation of the nuclear pore.Glucose-insulin-potassium solution protects ventricular myocytes of neonatal rat in an in vitro coverslip ischemia/reperfusion modelFatty acid synthase inhibits the O-GlcNAcase during oxidative stress.Exploration on mechanism of a new type of melatonin receptor agonist Neu-p11 in hypoxia-reoxygenation injury of myocardial cells.Ischemia/Reperfusion.Protein O-GlcNAcylation is a novel cytoprotective signal in cardiac stem cells.O-linked beta-N-acetylglucosamine (O-GlcNAc) regulates stress-induced heat shock protein expression in a GSK-3beta-dependent manner.
P2860
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P2860
Unique hexosaminidase reduces metabolic survival signal and sensitizes cardiac myocytes to hypoxia/reoxygenation injury.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Unique hexosaminidase reduces ...... hypoxia/reoxygenation injury.
@en
Unique hexosaminidase reduces ...... hypoxia/reoxygenation injury.
@nl
type
label
Unique hexosaminidase reduces ...... hypoxia/reoxygenation injury.
@en
Unique hexosaminidase reduces ...... hypoxia/reoxygenation injury.
@nl
prefLabel
Unique hexosaminidase reduces ...... hypoxia/reoxygenation injury.
@en
Unique hexosaminidase reduces ...... hypoxia/reoxygenation injury.
@nl
P2093
P2860
P1433
P1476
Unique hexosaminidase reduces ...... hypoxia/reoxygenation injury.
@en
P2093
Gladys A Ngoh
Heberty T Facundo
Natasha E Zachara
Steven P Jones
Tariq Hamid
Wolfgang Dillmann
P2860
P356
10.1161/CIRCRESAHA.108.189431
P577
2008-11-20T00:00:00Z