The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels
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Is TMC1 the Hair Cell Mechanotransducer Channel?Exome sequencing identifies a mutation in TMC1 as a novel cause of autosomal recessive nonsyndromic hearing lossThe effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cellsClass III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.Mechanically Activated Ion ChannelsA Novel C-Terminal CIB2 (Calcium and Integrin Binding Protein 2) Mutation Associated with Non-Syndromic Hearing Loss in a Hispanic FamilyConductance and block of hair-cell mechanotransducer channels in transmembrane channel-like protein mutantsThe murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.Synaptic transmission between end bulbs of Held and bushy cells in the cochlear nucleus of mice with a mutation in Otoferlin.The physiology of mechanoelectrical transduction channels in hearing.TMC function in hair cell transductionLocal mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells.Genetics of auditory mechano-electrical transduction.Designer aminoglycosides prevent cochlear hair cell loss and hearing lossSubunit determination of the conductance of hair-cell mechanotransducer channelsTransmembrane channel-like (tmc) gene regulates Drosophila larval locomotion.Mechanosensory hair cells express two molecularly distinct mechanotransduction channels.The transmembrane channel-like protein family and human papillomaviruses: Insights into epidermodysplasia verruciformis and progression to squamous cell carcinoma.CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.Characterization of transcriptomes of cochlear inner and outer hair cells.Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2Mutations of TMC1 cause deafness by disrupting mechanoelectrical transductionAdaptation Independent Modulation of Auditory Hair Cell Mechanotransduction Channel Open Probability Implicates a Role for the Lipid Bilayer.Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation.How many proteins does it take to gate hair cell mechanotransduction?TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell StereociliaAngular Approach Scanning Ion Conductance Microscopy.Development and localization of reverse-polarity mechanotransducer channels in cochlear hair cellsWho needs tip links? Backwards transduction by hair cellsMolecular Identity of the Mechanotransduction Channel in Hair Cells: Not Quiet There Yet.Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel.The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements.The how and why of identifying the hair cell mechano-electrical transduction channelThe molecules that mediate sensory transduction in the mammalian inner ear.The elusive mechanotransduction machinery of hair cells.Mechanosensitive Ion Channels in Cardiovascular PhysiologyTMIE is an essential component of the mechanotransduction machinery of cochlear hair cells.The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VIAre TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?Spatiotemporal changes in the distribution of LHFPL5 in mice cochlear hair bundles during development and in the absence of PCDH15.
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The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 14 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of transmembrane chan ...... ell mechanotransducer channels
@en
The role of transmembrane chan ...... ll mechanotransducer channels.
@nl
type
label
The role of transmembrane chan ...... ell mechanotransducer channels
@en
The role of transmembrane chan ...... ll mechanotransducer channels.
@nl
prefLabel
The role of transmembrane chan ...... ell mechanotransducer channels
@en
The role of transmembrane chan ...... ll mechanotransducer channels.
@nl
P2093
P2860
P356
P1476
The role of transmembrane chan ...... ell mechanotransducer channels
@en
P2093
Carole M Hackney
David N Furness
Kyunghee X Kim
Robert Fettiplace
Shanthini Mahendrasingam
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P304
P356
10.1085/JGP.201311068
P577
2013-10-14T00:00:00Z