Factor XI contributes to thrombin generation in the absence of factor XII - Wikidata - awgldk - TriplyDB

Factor XI contributes to thrombin generation in the absence of factor XII

Factor XI contributes to thrombin generation in the absence of factor XII

http://www.wikidata.org/entity/Q37271059

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In microfluidico: Recreating in vivo hemodynamics using miniaturized devices A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo The mechanism underlying activation of factor IX by factor XIa.Activated factor V is a cofactor for the activation of factor XI by thrombin in plasma.Structure and function of factor XI Increased promyelocytic-derived microparticles: a novel potential factor for coagulopathy in acute promyelocytic leukemia.Genetic variants of coagulation factor XI show association with ischemic stroke up to 70 years of age.Activation of factor XI by products of prothrombin activation Activated factor XI increases the procoagulant activity of the extrinsic pathway by inactivating tissue factor pathway inhibitor Laminin promotes coagulation and thrombus formation in a factor XII-dependent manner.Regulation of coagulation factor XI expression by microRNAs in the human liver Notecarin D binds human factor V and factor Va with high affinity in the absence of membranes.Polyphosphate is a cofactor for the activation of factor XI by thrombin.Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants.Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis.FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI.A sequential mechanism for exosite-mediated factor IX activation by factor XIa Thrombin activity propagates in space during blood coagulation as an excitation wave.P1 and P2' site mutations convert protease nexin-2 from a factor XIa inhibitor to a plasmin inhibitor Coagulation Factor XI Promotes Distal Platelet Activation and Single Platelet Consumption in the Bloodstream Under Shear Flow.A comparison of the effects of factor XII deficiency and prekallikrein deficiency on thrombus formation.Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates.Why factor XI deficiency is a clinical concern.Evidence for factor IX-independent roles for factor XIa in blood coagulation.Factor XII inhibition reduces thrombus formation in a primate thrombosis model.Coagulation factor XI as a novel target for antithrombotic treatment.The many faces of the contact pathway and their role in thrombosis.Factor XI and XII as antithrombotic targets.The procoagulant and proinflammatory plasma contact system.The hemostatic role of factor XI.Differential Roles for the Coagulation Factors XI and XII in Regulating the Physical Biology of Fibrin.Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.Factor XI deficiency enhances the pulmonary allergic response to house dust mite in mice independent of factor XII.Hypercoagulability and the risk of myocardial infarction and ischemic stroke in young women.Acquired factor XI deficiency in a child with membranoproliferative glomerulonephritis.Evidence against a protein in plasma that is a product of a factor XI mRNA splice variant missing exons 6 and 7.Dynamics of Thrombin Generation and Flux from Clots during Whole Human Blood Flow over Collagen/Tissue Factor Surfaces.Targeting factor XI to prevent thrombosis

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Factor XI contributes to thrombin generation in the absence of factor XII

http://www.wikidata.org/entity/Q37271059

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 07 April 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Factor XI contributes to thrombin generation in the absence of factor XII

@en

Factor XI contributes to thrombin generation in the absence of factor XII.

@nl

type

label

Factor XI contributes to thrombin generation in the absence of factor XII

@en

Factor XI contributes to thrombin generation in the absence of factor XII.

@nl

prefLabel

Factor XI contributes to thrombin generation in the absence of factor XII

@en

Factor XI contributes to thrombin generation in the absence of factor XII.

@nl

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BLOOD-2009-02-203604

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Factor XI contributes to thrombin generation in the absence of factor XII

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Anton Matafonov

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David Gailani

http://www.w3.org/2001/XMLSchema#string

Dmitri V Kravtsov

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Erik I Tucker

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Mao-Fu Sun

http://www.w3.org/2001/XMLSchema#string

Peter N Walsh

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P2860

Defective thrombus formation in mice lacking coagulation factor XII

Regulation of coagulation by a multivalent Kunitz-type inhibitor

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

The coagulation cascade: initiation, maintenance, and regulation

Activation of human blood coagulation factor XI independent of factor XII. Factor XI is activated by thrombin and factor XIa in the presence of negatively charged surfaces

Factor XII-independent activation of factor XI in plasma: effects of sulfatides on tissue factor-induced coagulation

Thrombin activates factor XI on activated platelets in the absence of factor XII

Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation.

Polyphosphate modulates blood coagulation and fibrinolysis.

Factor XI activation in a revised model of blood coagulation.

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452-458

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scholarly article

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10.1182/BLOOD-2009-02-203604

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2

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19351955

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