HFE C282Y homozygotes are at increased risk of breast and colorectal cancer - Wikidata - awgldk - TriplyDB

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

http://www.wikidata.org/entity/Q37274209

about

Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field Cancer cells with irons in the fire Evidence for the Influence of the Iron Regulatory MHC Class I Molecule HFE on Tumor Progression in Experimental Models and Clinical Populations Iron and cancer: more ore to be mined.Dietary iron, iron homeostatic gene polymorphisms and the risk of advanced colorectal adenoma and cancer.Pathophysiological consequences and benefits of HFE mutations: 20 years of research.HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function.Effects of iron deficiency and iron overload on angiogenesis and oxidative stress-a potential dual role for iron in breast cancer Insights into the pathogenesis and treatment of cancer from inborn errors of metabolism.Gastrins, iron homeostasis and colorectal cancer Iron homeostasis and tumorigenesis: molecular mechanisms and therapeutic opportunities C282Y-HFE gene variant affects cholesterol metabolism in human neuroblastoma cells Oh the irony: Iron as a cancer cause or cure?National Cancer Institute-National Heart, Lung and Blood Institute/pediatric Blood and Marrow Transplant Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: long-term organ damage a Impact of hemochromatosis gene (HFE) mutations on epithelial ovarian cancer risk and prognosis Analysis of single nucleotide variants of HFE gene and association to survival in The Cancer Genome Atlas GBM data Hemochromatosis (HFE) gene mutations and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.The risk of new-onset cancer associated with HFE C282Y and H63D mutations: evidence from 87,028 participants Cellular iron metabolism in prognosis and therapy of breast cancer.Intestinal iron homeostasis and colon tumorigenesis Toenail iron, genetic determinants of iron status, and the risk of glioma Premenopausal plasma ferritin levels, HFE polymorphisms, and risk of breast cancer in the nurses' health study II.DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms.Review article: the iron overload syndromes.Diagnosis and treatment of hereditary hemochromatosis: an update.Dietary Iron and Colorectal Cancer Risk: A Review of Human Population Studies.Deferasirox has strong anti-leukemia activity but may antagonize theanti-leukemia effect of doxorubicin.Overview of iron metabolism in health and disease.The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system Effect of HFE variants on sphingolipid expression by SH-SY5Y human neuroblastoma cells.HFE polymorphisms influence the response to chemotherapeutic agents via induction of p16INK4A.Haemochromatosis and gastrointestinal cancer.Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis HFE polymorphisms affect survival of brain tumor patients.Iron: an emerging factor in colorectal carcinogenesis.HFE gene C282Y variant is associated with colorectal cancer in Caucasians: a meta-analysis.H63D HFE polymorphisms are associated with increased disease duration and decreased muscle superoxide dismutase-1 expression in amyotrophic lateral sclerosis patients.Cancer risk in HFE C282Y homozygotes: results from the HUNT 2 study.Iron chelation: an adjuvant therapy to target metabolism, growth and survival of murine PTEN-deficient T lymphoma and human T lymphoblastic leukemia/lymphoma.

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HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

http://www.wikidata.org/entity/Q37274209

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on April 2010

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

@en

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer.

@nl

type

label

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

@en

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer.

@nl

prefLabel

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

@en

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer.

@nl

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HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

@en

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Christine E McLaren

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Clare C Constantine

http://www.w3.org/2001/XMLSchema#string

Dorota M Gertig

http://www.w3.org/2001/XMLSchema#string

Lawrie W Powell

http://www.w3.org/2001/XMLSchema#string

Martin B Delatycki

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P2860

Hereditary hemochromatosis in the post-HFE era

Assignment of the human cyclin D3 gene (CCND3) to chromosome 6p----q13

Iron-overload-related disease in HFE hereditary hemochromatosis

Uncommon mutations and polymorphisms in the hemochromatosis gene.

Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases.

Iron, radiation, and cancer

Physical activity, insulin-like growth factor 1, insulin-like growth factor binding protein 3, and survival from colorectal cancer

Chromosome 6p amplification and cancer progression.

Iron overload and immunity.

HFE C282Y/H63D compound heterozygotes are at low risk of hemochromatosis-related morbidity.

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1311-1318

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scholarly article

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10.1002/HEP.23448

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4

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51

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Graham G. Giles

Nicholas J. Osborne

Dallas R. English

Melissa C. Southey

Gregory J Anderson

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2010-04-01T00:00:00Z

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41124685

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20099304

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colorectal cancer

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3815603

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