Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
about
The biological sense of cancer: a hypothesisWhy don't we get more cancer? A proposed role of the microenvironment in restraining cancer progressionOf extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene.An odyssey from breast to bone: multi-step control of mammary metastases and osteolysis by matrix metalloproteinases.The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D culturesPlasticity of mammary epithelia during normal development and neoplastic progression.Physiological roles of matrix metalloproteinases: implications for tumor growth and metastasis.Perturbation of beta1-integrin function alters the development of murine mammary gland.Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer.Proteinases, cell cycle regulation, and apoptosis during mammary gland involution (minireview).The importance of the microenvironment in breast cancer progression: recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay.Transcriptional regulation of stromelysin-1 gene expression is altered during progression of mouse mammary epithelial cells from functionally normal to malignant.Communication between the cell membrane and the nucleus: role of protein compartmentalization.Order and disorder: the role of extracellular matrix in epithelial cancer.Extracellular matrix remodeling and the regulation of epithelial-stromal interactions during differentiation and involutionRadiation and the microenvironment - tumorigenesis and therapy.The not-so innocent bystander: the microenvironment as a therapeutic target in cancer.Tissue architecture: the ultimate regulator of epithelial function?Expression of autoactivated stromelysin-1 in mammary glands of transgenic mice leads to a reactive stroma during early development.Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases.Matrix metalloproteinases as breast cancer drivers and therapeutic targets.Tumour-stromal interactions in breast cancer: the role of stroma in tumourigenesis.Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells.Insulin-like growth factor II signaling in neoplastic proliferation is blocked by transgenic expression of the metalloproteinase inhibitor TIMP-1.Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2.Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancersThe metastasis-promoting protein S100A4 regulates mammary branching morphogenesis.Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitroExpression of Hoxa-1 and Hoxb-7 is regulated by extracellular matrix-dependent signals in mammary epithelial cells.Epimorphin is a novel regulator of the progesterone receptor isoform-a.Mammary involution and breast cancer risk: transgenic models and clinical studies.The extracellular matrix in epithelial biology: shared molecules and common themes in distant phyla.Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle.Targeting stroma to treat cancers.Metastasis review: from bench to bedside.Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.Involvement of matrix metalloproteinase type-3 in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cells.Glandular structure and gene expression. Lessons from the mammary gland.
P2860
Q28763945-8D008091-5A82-4519-B0CB-016C4DA2F6FEQ29614274-F8791954-42E4-4F3C-8D95-74AB15D26025Q30355361-412E442D-FCD0-49E0-8F76-E24BAF48E138Q30442174-6488C8A5-657D-4B52-BF38-949AED3E8B00Q33586496-78F242F8-65A5-4ACE-88CC-108E30E42C7CQ33596766-19F85E27-7EA1-4FDF-93E4-3E3DFCC7A43AQ33678437-DCE27915-EFFD-41C1-9F5B-FAC08C54919CQ33760250-9ECCF625-4FD3-443B-8660-9A1AC89BBA75Q33888649-06BE0F2F-83CC-4E60-87E8-BB3005EAA169Q33915005-0F65B6EB-4E7B-4732-A525-9AAA54A2E773Q33980660-5A60E1F3-7F45-4DFE-82EC-4D1590573ED9Q34103339-AB2EC0BE-57CA-40ED-A0A6-AE966F97F97BQ34103350-E09ADA26-8E4E-4069-8FFF-014A90CD6E86Q34103406-3960E8C2-7B47-47BC-9776-AD45E6BBA483Q34103413-9BA396A1-A33F-4500-9E29-8D294645CCAAQ34117340-CFF655FB-44A1-44CA-971B-6521989FB868Q34472892-D040E244-5092-4705-A242-CDE72AED25A8Q35056031-CF2B1BDC-E796-4CE1-A229-8E52BB9B2250Q35212052-3B838A6D-F126-4FE6-9C87-5EF3D0C1D415Q35753309-D56BDB32-E49D-4D06-92D8-0439F2BDA171Q35762816-47D11EB7-3217-4A36-9AA9-5AE746B8F899Q35892721-AE87C890-AB92-409E-B491-9408BF46F385Q36188568-DE0D54B5-DF80-4C04-B8AF-0C288F38FDD3Q36255048-1BBA32DF-672B-4010-9966-DF6CEAD5DD2CQ36301466-E144E284-FD8A-4E14-97A2-DBF5CEFB5103Q36498019-55999EDA-8DB9-4931-A9AF-5470B4F050B8Q36622753-F6C22211-8363-42BA-8BA5-67C8F52663B8Q36814092-D66AEE2F-3D3D-4C61-B540-D7249C575034Q36837467-8EE6F7E4-029D-4BCD-B3D1-C2FF572284B7Q36897024-ACCF55FB-2702-499E-B24E-8ACA3666863DQ37198024-5A0CB9C8-46DA-417D-A68D-3536FF5934A6Q37220983-906F1EAC-C67B-4B84-A8E8-F65C7D63C612Q37274385-08FF578E-A46E-4F37-836E-8D52E0A58278Q37659597-C86A5546-F4A6-44B1-B6B2-64EE8DB49503Q37972797-9A63275B-A398-469E-9B8B-A2ED004A20DAQ38237985-F192EE11-E6F7-49B1-9D57-D9700DE93F6FQ42720277-73EEF214-DF3C-4FBF-A169-CD2970C71503Q43144068-54C2D19D-741E-4645-8369-363D19763FEBQ43844074-94DEFC84-7C12-49A8-9FBE-A8F8C903EA51Q44897817-A8E0720A-C201-44FD-B7AF-79226DCA85A7
P2860
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1995
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
@en
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
@nl
type
label
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
@en
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
@nl
prefLabel
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
@en
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
@nl
P2093
P2860
P356
P1476
Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.
@en
P2093
P2860
P304
P356
10.1006/SCBI.1995.0022
P577
1995-06-01T00:00:00Z