Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer. - Wikidata - awgldk - TriplyDB

Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer.

Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer.

http://www.wikidata.org/entity/Q37277170

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Oncogenic role of leptin and Notch interleukin-1 leptin crosstalk outcome in cancer Adipocytes: impact on tumor growth and potential sites for therapeutic intervention The balance between leptin and adiponectin in the control of carcinogenesis - focus on mammary tumorigenesis Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells The integrative role of leptin, oestrogen and the insulin family in obesity-associated breast cancer: potential effects of exercise Obesity and cancer: at the crossroads of cellular metabolism and proliferation The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression Glioblastoma-derived leptin induces tube formation and growth of endothelial cells: comparison with VEGF effects Leptin-Notch signaling axis is involved in pancreatic cancer progression Leptin is overexpressed in the tumor microenvironment of obese patients with estrogen receptor positive breast cancer.Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer.Leptin signaling and apoptotic effects in human prostate cancer cell lines.Vascular endothelial growth factor receptor-2 in breast cancer.NILCO biomarkers in breast cancer from Chinese patients Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/VEGFR-2 expression in breast cancer.Association of serum soluble leptin receptor and leptin levels with breast cancer Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFkappaB/HIF-1alpha activation New pharmacological perspectives for the leptin receptor in the treatment of obesity The role of obesity in oesophageal cancer development.Effects of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma in plasminogen activator inhibitor-1 deficient and wild-type mice.Regenerative therapy after cancer: what are the risks?Biology of obesity: lessons from animal models of obesity Pathophysiological mechanisms linking obesity and esophageal adenocarcinoma Leptin signaling molecular actions and drug target in hepatocellular carcinoma Leptin pro-angiogenic signature in breast cancer is linked to IL-1 signalling.Leptin promotes melanoma tumor growth in mice related to increasing circulating endothelial progenitor cells numbers and plasma NO production Role of Notch and its oncogenic signaling crosstalk in breast cancer.Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway The anti-tumor activity of a neutralizing nanobody targeting leptin receptor in a mouse model of melanoma.Obesity and breast cancer survival in ethnically diverse postmenopausal women: the Multiethnic Cohort Study Paracrine Interactions between Adipocytes and Tumor Cells Recruit and Modify Macrophages to the Mammary Tumor Microenvironment: The Role of Obesity and Inflammation in Breast Adipose Tissue Curcumin inhibits leptin gene expression and secretion in breast cancer cells by estrogen receptors.Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.A novel leptin antagonist peptide inhibits breast cancer growth in vitro and in vivo.The role of adipose-derived stem cells in breast cancer progression and metastasis.Adipocyte activation of cancer stem cell signaling in breast cancer Exogenous estrogen protects mice from the consequences of obesity and alcohol.Diabetic angiopathy and angiogenic defects.Inhibition of leptin gene expression and secretion by silibinin: possible role of estrogen receptors.Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.

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Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer.

http://www.wikidata.org/entity/Q37277170

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 16 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Leptin-signaling inhibition re ...... ive or negative breast cancer.

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Leptin-signaling inhibition re ...... ive or negative breast cancer.

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Leptin-signaling inhibition re ...... ive or negative breast cancer.

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Leptin-signaling inhibition re ...... ive or negative breast cancer.

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Leptin-signaling inhibition re ...... ive or negative breast cancer.

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Leptin-signaling inhibition re ...... ive or negative breast cancer.

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Breast Cancer Research

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Leptin-signaling inhibition re ...... ive or negative breast cancer.

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Amber Watters

http://www.w3.org/2001/XMLSchema#string

Bo R Rueda

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David R Mann

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Manuel L Penichet

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Ruben Rene Gonzalez

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Udai P Singh

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Yanbo Xu

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P2860

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults

The leptin receptor

Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)

Leptin regulation of proangiogenic molecules in benign and cancerous endometrial cells.

Side effects of adjuvant treatment of breast cancer.

Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor

Leptin and cancer.

Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression.

Ablation of leptin signaling disrupts the establishment, development, and maintenance of endometriosis-like lesions in a murine model.

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10.1186/BCR2321

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