Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions. - Wikidata - awgldk - TriplyDB

Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions.

Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions.

http://www.wikidata.org/entity/Q37283796

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Establishing biomechanical mechanisms in mouse models: practical guidelines for systematically evaluating phenotypic changes in the diaphyses of long bones Liver-derived IGF-I regulates mean life span in mice Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway.Bone mineral density in partially recovered early onset anorexic patients - a follow-up investigation.Update in new anabolic therapies for osteoporosis Insulin-like growth factor 1 physiology: lessons from mouse models.Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis.Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies.Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis.The effects of n-3 long-chain polyunsaturated fatty acids on bone formation and growth factors in adolescent boys.Does dietary protein reduce hip fracture risk in elders? The Framingham Osteoporosis Study.Determinants of bone microarchitecture and mechanical properties in obese men Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth.Growth factor control of bone mass.Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner.Deficiency of retinaldehyde dehydrogenase 1 induces BMP2 and increases bone mass in vivo.Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils Sex-specific regulation of body size and bone slenderness by the acid labile subunit Elevated serum IGF-1 levels synergize PTH action on the skeleton only when the tissue IGF-1 axis is intact.Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1.Genetically determined phenotype covariation networks control bone strength IGF-1 and bone: New discoveries from mouse models Unbound (bioavailable) IGF1 enhances somatic growth.Update on bone anabolics in osteoporosis treatment: rationale, current status, and perspectives New treatment modalities in osteoporosis.Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels.Insulin Resistance Negatively Influences the Muscle-Dependent IGF-1-Bone Mass Relationship in Premenarcheal Girls A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models.IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms.Increased diet-induced fatty streak formation in female mice with deficiency of liver-derived insulin-like growth factor-I.Growth hormone is positively associated with surrogate markers of bone turnover during puberty.Systemically delivered insulin-like growth factor-I enhances mesenchymal stem cell-dependent fracture healing.Different effects on bone strength and cell differentiation in pre pubertal caloric restriction versus hypothalamic suppression.Low levels of plasma IGF-1 inhibit intracortical bone remodeling during aging Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice.Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor.The polymorphism of Insulin-like growth factor-I (IGF-I) is related to osteoporosis and bone mineral density in postmenopausal population Skeletal biology over the life span: a view from the surfaces.Signaling pathways affecting skeletal health.

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Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions.

http://www.wikidata.org/entity/Q37283796

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article científic

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bilimsel makale

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scientific article published on August 2009

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Serum IGF-1 determines skeleta ...... ansion and trait interactions.

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Serum IGF-1 determines skeleta ...... ansion and trait interactions.

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Serum IGF-1 determines skeleta ...... ansion and trait interactions.

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Serum IGF-1 determines skeleta ...... ansion and trait interactions.

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Serum IGF-1 determines skeleta ...... ansion and trait interactions.

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Serum IGF-1 determines skeleta ...... ansion and trait interactions.

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Journal of Bone and Mineral Research

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Serum IGF-1 determines skeleta ...... ansion and trait interactions.

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Clifford Rosen

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Ernesto Canalis

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Hayden-William Courtland

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Hui Sun

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Karl J Jepsen

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Philip Nasser

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Shoshana Yakar

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Valerie Williams

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Wilson Mejia

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Yuki Kawashima

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P2860

Osteoimmunology: interactions of the bone and immune system

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Construction of the femoral neck during growth determines its strength in old age.

Femoral neck BMD is a strong predictor of hip fracture susceptibility in elderly men and women because it detects cortical bone instability: the Rotterdam Study.

Impaired skeletal growth in mice with haploinsufficiency of IGF-I: genetic evidence that differences in IGF-I expression could contribute to peak bone mineral density differences.

Circulating levels of IGF-1 directly regulate bone growth and density.

Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.

Defining the genetics of osteoporosis: using the mouse to understand man.

Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction.

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1481-1492

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scholarly article

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10.1359/JBMR.090226

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8

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24

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Ernesto Canalis

Mary L Bouxsein

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2009-08-01T00:00:00Z

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24174170

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19257833

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2718800

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