Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction.
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Rescuing loading induced bone formation at senescenceLoad-induced changes in bone stiffness and cancellous and cortical bone mass following tibial compression diminish with age in female miceHypoxia-inducible factor-1α protein negatively regulates load-induced bone formationEffects of Loading Duration and Short Rest Insertion on Cancellous and Cortical Bone Adaptation in the Mouse TibiaLocal mechanical stimuli regulate bone formation and resorption in mice at the tissue level.Knee loading stimulates cortical bone formation in murine femursSmall oscillatory accelerations, independent of matrix deformations, increase osteoblast activity and enhance bone morphology.Stress and Alterations in Bones: An Interdisciplinary PerspectiveFunctional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones.Effect of aging on cellular mechanotransductionBiomimetic bone mechanotransduction modeling in neonatal rat femur organ cultures: structural verification of proof of concept.Remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induces periosteal cell proliferation during bone formation.In vivo tibial stiffness is maintained by whole bone morphology and cross-sectional geometry in growing female mice.The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in BoneEnhancement of implant osseointegration by high-frequency low-magnitude loadingLow-magnitude mechanical loading becomes osteogenic when rest is inserted between each load cycle.Botox induced muscle paralysis rapidly degrades bone.Swimming enhances bone mass acquisition in growing female rats.Experimental and finite element analysis of dynamic loading of the mouse forearmMegakaryocytes are mechanically responsive and influence osteoblast proliferation and differentiationRest intervals reduce the number of loading bouts required to enhance bone formation.Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loadingLoad/strain distribution between ulna and radius in the mouse forearm compression loading model.Design and analysis of a novel mechanical loading machine for dynamic in vivo axial loading.Mechanical load increases in bone formation via a sclerostin-independent pathway.Bone mechanotransduction may require augmentation in order to strengthen the senescent skeleton.In vivo assessment of the effect of controlled high- and low-frequency mechanical loading on peri-implant bone healingMechanical regulation of signaling pathways in bone.Numerical modeling of long bone adaptation due to mechanical loading: correlation with experiments.Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms.Molecular pathways mediating mechanical signaling in bone.Preclinical mouse models for assessing axial compression of long bones during exercise.Bone strength: current concepts.Activation of the IGF1 pathway mediates changes in cellular contractility and motility in single-suture craniosynostosis.32 wk old C3H/HeJ mice actively respond to mechanical loading.Male mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight.Differences in trabecular bone of leptin-deficient ob/ob mice in response to biomechanical loadingRegulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models.The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading.Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions.
P2860
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P2860
Noninvasive loading of the murine tibia: an in vivo model for the study of mechanotransduction.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Noninvasive loading of the mur ...... study of mechanotransduction.
@ast
Noninvasive loading of the mur ...... study of mechanotransduction.
@en
Noninvasive loading of the mur ...... study of mechanotransduction.
@nl
type
label
Noninvasive loading of the mur ...... study of mechanotransduction.
@ast
Noninvasive loading of the mur ...... study of mechanotransduction.
@en
Noninvasive loading of the mur ...... study of mechanotransduction.
@nl
prefLabel
Noninvasive loading of the mur ...... study of mechanotransduction.
@ast
Noninvasive loading of the mur ...... study of mechanotransduction.
@en
Noninvasive loading of the mur ...... study of mechanotransduction.
@nl
P2093
P2860
P1476
Noninvasive loading of the mur ...... study of mechanotransduction.
@en
P2093
Chung C Liu
Steven D Bain
Sundar Srinivasan
Ted S Gross
Thomas L Clemens
P2860
P304
P356
10.1359/JBMR.2002.17.3.493
P577
2002-03-01T00:00:00Z