Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status.
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Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary fieldGene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolismOne-carbon metabolism and Alzheimer's disease: focus on epigeneticsDifferent patterns of DNA methylation of the two distinct O6-methylguanine-DNA methyltransferase (O6-MGMT) promoter regions in colorectal cancer.Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer.The 677C>T (rs1801133) polymorphism in the MTHFR gene contributes to colorectal cancer risk: a meta-analysis based on 71 research studies.Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and womenThe influence of one-carbon metabolism on gene promoter methylation in a population-based breast cancer study.Folate Intake, MTHFR Polymorphisms, and the Risk of Colorectal Cancer: A Systematic Review and Meta-AnalysisConcentration of folate in colorectal tissue biopsies predicts prevalence of adenomatous polyps.Precancerous lesions in colorectal cancer.MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patientsSystematic review of adverse health outcomes associated with high serum or red blood cell folate concentrationsAssociation of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms with colorectal cancer risk: A meta-analysis.Association of MTHFR C677T polymorphisms and colorectal cancer risk in Asians: evidence of 12,255 subjects.Association Between MTHFR Genetic Variants and Multiple Sclerosis in a Southern Iranian Population.Tyms double (2R) and triple repeat (3R) confers risk for human oral squamous cell carcinoma.Folate intake and the risk of colorectal cancer in a Korean population.Methylenetetrahydrofolate reductase C677T polymorphism and colorectal cancer susceptibility: a meta-analysis.Association of folate and other one-carbon related nutrients with hypermethylation status and expression of RARB, BRCA1, and RASSF1A genes in breast cancer patients.MTHFR rs1801133 polymorphism and susceptibility to colorectal cancer in Iranian population: evidence of a case-control study and meta-analysis.Association study of the common polymorphisms in the folate-methionine pathway with retinoblastoma.Epigenetic and genetic analysis of WNT signaling pathway in sporadic colorectal cancer patients from Iran.Reduced levels of folate transporters (PCFT and RFC) in membrane lipid rafts result in colonic folate malabsorption in chronic alcoholism.High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.
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P2860
Methylenetetrahydrofolate reductase C677T genotype affects promoter methylation of tumor-specific genes in sporadic colorectal cancer through an interaction with folate/vitamin B12 status.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Methylenetetrahydrofolate redu ...... ith folate/vitamin B12 status.
@en
Methylenetetrahydrofolate redu ...... ith folate/vitamin B12 status.
@nl
type
label
Methylenetetrahydrofolate redu ...... ith folate/vitamin B12 status.
@en
Methylenetetrahydrofolate redu ...... ith folate/vitamin B12 status.
@nl
prefLabel
Methylenetetrahydrofolate redu ...... ith folate/vitamin B12 status.
@en
Methylenetetrahydrofolate redu ...... ith folate/vitamin B12 status.
@nl
P2093
P2860
P50
P921
P356
P1476
Methylenetetrahydrofolate redu ...... ith folate/vitamin B12 status.
@en
P2093
Abdoulrasool Talei
Fakhraddin Naghibalhossaini
Heshmetalah Salahi
Mehdi Saberi Firoozi
Mehra Mojallal
Seyed Ali Malek-Hosseini
P2860
P304
P356
10.3748/WJG.14.3662
P407
P577
2008-06-01T00:00:00Z