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Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancerSulfonylurea receptor 1 in central nervous system injury: a focused reviewFoxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expressionIdentification of the 'NORE' (N-Oct-3 responsive element), a novel structural motif and composite element.Hyperinsulinemic Hypoglycemia - The Molecular MechanismsMicroRNAs in insulin resistance and obesityThe MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.Functional diversification of paralogous transcription factors via divergence in DNA binding site motif and in expressionDetection of molecular paths associated with insulitis and type 1 diabetes in non-obese diabetic mouseIdentification of known and novel pancreas genes expressed downstream of Nkx2.2 during developmentFoxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cellsMolecular mechanisms of protein induced hyperinsulinaemic hypoglycaemia.Foxa2 is essential for mouse endometrial gland development and fertility.Enhancement of insulin-producing cell differentiation from embryonic stem cells using pax4-nucleofection method.Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cellTranscriptional regulation of α-cell differentiation.Islet-1 Is essential for pancreatic β-cell function.Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation.Fat mass and obesity associated gene (FTO) expression is regulated negatively by the transcription factor Foxa2.Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrityTranscriptional effects of E3 ligase atrogin-1/MAFbx on apoptosis, hypertrophy and inflammation in neonatal rat cardiomyocytes.Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress.Genetic variants of FOXA2: risk of type 2 diabetes and effect on metabolic traits in North Indians.Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.FOXA1: master of steroid receptor function in cancer.A small molecule differentiation inducer increases insulin production by pancreatic β cellsExpansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alphaSequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8.Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell functionOrganogenesis and functional genomics of the endocrine pancreasDietary selenium deficiency partially rescues type 2 diabetes-like phenotypes of glutathione peroxidase-1-overexpressing male mice.In control of biology: of mice, men and FoxesGenome-wide association study of 25(OH) Vitamin D concentrations in Punjabi Sikhs: Results of the Asian Indian diabetic heart study.Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencingUncoupling proteins: role in insulin resistance and insulin insufficiencyRole of microRNAs in diabetes.On the origin of the beta cell.Molecular medicine of microRNAs: structure, function and implications for diabetes.Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.Insulin acts through FOXO3a to activate transcription of plasminogen activator inhibitor type 1.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Foxa2 regulates multiple pathways of insulin secretion.
@en
Foxa2 regulates multiple pathways of insulin secretion.
@nl
type
label
Foxa2 regulates multiple pathways of insulin secretion.
@en
Foxa2 regulates multiple pathways of insulin secretion.
@nl
prefLabel
Foxa2 regulates multiple pathways of insulin secretion.
@en
Foxa2 regulates multiple pathways of insulin secretion.
@nl
P2093
P2860
P1476
Foxa2 regulates multiple pathways of insulin secretion
@en
P2093
Franz M Matschinsky
John E Brestelli
Joshua R Friedman
Klaus H Kaestner
Kristen A Lantz
P2860
P304
P356
10.1172/JCI200421149
10.1172/JCI21149
P407
P577
2004-08-01T00:00:00Z