Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. - Wikidata - awgldk - TriplyDB

Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.

Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.

http://www.wikidata.org/entity/Q37291657

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A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization Transcriptional network control of normal and leukaemic haematopoiesis Cell-type-specific activation and repression of PU.1 by a complex of discrete, functionally specialized cis-regulatory elements The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish.Megakaryopoiesis PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN FOG1 requires NuRD to promote hematopoiesis and maintain lineage fidelity within the megakaryocytic-erythroid compartment.Mathematical modeling of GATA-switching for regulating the differentiation of hematopoietic stem cell.Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells Divergent functions of hematopoietic transcription factors in lineage priming and differentiation during erythro-megakaryopoiesis GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia.Transcription factor networks in erythroid cell and megakaryocyte development Spectrum of myeloid neoplasms and immune deficiency associated with germline GATA2 mutations.Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia.PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 Transcription in Dendritic Cells.A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.Early mammalian erythropoiesis requires the Dot1L methyltransferase Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis.GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in Erythroleukemia Distinct gene expression program dynamics during erythropoiesis from human induced pluripotent stem cells compared with adult and cord blood progenitors.Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia.Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3.Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling Long and short non-coding RNAs as regulators of hematopoietic differentiation Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors.Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly.Histone methylation in myelodysplastic syndromes.Epigenetic and genetic mechanisms in red cell biology.Ncor1 and Ncor2 play essential but distinct roles in zebrafish primitive myelopoiesis.Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1.Mechanisms of self-renewal in hematopoietic stem cells.2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.Down-regulation of hematopoiesis master regulator PU.1 via aberrant methylation in chronic myeloid leukemia.Transcriptional regulation of Elf-1: locus-wide analysis reveals four distinct promoters, a tissue-specific enhancer, control by PU.1 and the importance of Elf-1 downregulation for erythroid maturation

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Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.

http://www.wikidata.org/entity/Q37291657

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 02 June 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Graded repression of PU.1/Sfpi ...... lates hematopoietic cell fate.

@en

Graded repression of PU.1/Sfpi ...... lates hematopoietic cell fate.

@nl

type

label

Graded repression of PU.1/Sfpi ...... lates hematopoietic cell fate.

@en

Graded repression of PU.1/Sfpi ...... lates hematopoietic cell fate.

@nl

prefLabel

Graded repression of PU.1/Sfpi ...... lates hematopoietic cell fate.

@en

Graded repression of PU.1/Sfpi ...... lates hematopoietic cell fate.

@nl

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Graded repression of PU.1/Sfpi ...... lates hematopoietic cell fate.

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Eugene Khandros

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Gerd A Blobel

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Kim E Nichols

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L Charles Bailey

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Stella T Chou

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Yu Yao

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P2860

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

GATA-1 forms distinct activating and repressive complexes in erythroid cells

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Exploring the full spectrum of macrophage activation

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1

PU.1 (Spi-1) autoregulates its expression in myeloid cells

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

Novel combinatorial interactions of GATA-1, PU.1, and C/EBPepsilon isoforms regulate transcription of the gene encoding eosinophil granule major basic protein

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983-994

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scholarly article

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10.1182/BLOOD-2009-03-207944

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5

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114

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Christopher R. Vakoc

John D Crispino

Mitchell J Weiss

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2009-06-02T00:00:00Z

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26261959

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19491391

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2721792

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