Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction.
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What global diastolic function is, what it is not, and how to measure itTitin and desmosomal genes in the natural history of arrhythmogenic right ventricular cardiomyopathyProtein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative foldingGenetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathy.Time-Dependent Regional Myocardial Strains in Patients with Heart Failure with a Preserved Ejection Fraction.S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding.Advances in the pathophysiology and treatment of heart failure with preserved ejection fractionDeveloping therapies for heart failure with preserved ejection fraction: current state and future directionsExperimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.Heart failure with preserved ejection fraction: molecular pathways of the aging myocardiumDeleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.Arrhythmogenic right ventricular cardiomyopathy: From genetics to diagnostic and therapeutic challenges.Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodelingMyocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titinPhosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle ForceExercise Intolerance In Heart Failure With Preserved Ejection Fraction.Removal of immunoglobulin-like domains from titin's spring segment alters titin splicing in mouse skeletal muscle and causes myopathy.New insights in (inter)cellular mechanisms by heart failure with preserved ejection fraction.The genetic landscape of cardiomyopathy and its role in heart failure.Cardiac Physiology of Aging: Extracellular Considerations.Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins.Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model (TtnΔIAjxn)The giant protein titin regulates the length of the striated muscle thick filament.Hypothesis and theory: mechanical instabilities and non-uniformities in hereditary sarcomere myopathies.Placenta-Derived Adherent Stromal Cells Improve Diabetes Mellitus-Associated Left Ventricular Diastolic Performance.An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.Relaxation and the Role of Calcium in Isolated Contracting Myocardium From Patients With Hypertensive Heart Disease and Heart Failure With Preserved Ejection Fraction.The link between exercise and titin passive stiffness.Disulfide isomerization reactions in titin immunoglobulin domains enable a mode of protein elasticity.Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.Chronic low-intensity exercise attenuates cardiomyocyte contractile dysfunction and impaired adrenergic responsiveness in aortic-banded mini-swine.Left ventricular diastolic dysfunction and myocardial stiffness in diabetic mice is attenuated by inhibition of dipeptidyl peptidase 4.Current Perspectives on Systemic Hypertension in Heart Failure with Preserved Ejection Fraction.Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling.SMYD2 glutathionylation contributes to degradation of sarcomeric proteins
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Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Shortening of the elastic tand ...... eads to diastolic dysfunction.
@en
Shortening of the elastic tand ...... eads to diastolic dysfunction.
@nl
type
label
Shortening of the elastic tand ...... eads to diastolic dysfunction.
@en
Shortening of the elastic tand ...... eads to diastolic dysfunction.
@nl
prefLabel
Shortening of the elastic tand ...... eads to diastolic dysfunction.
@en
Shortening of the elastic tand ...... eads to diastolic dysfunction.
@nl
P2860
P50
P1433
P1476
Shortening of the elastic tand ...... eads to diastolic dysfunction.
@en
P2860
P356
10.1161/CIRCULATIONAHA.112.001268
P4011
26aa19beab519e7c3056e9b7e12dacc94ae9923a
P407
P50
P577
2013-05-24T00:00:00Z