CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection. - Wikidata - awgldk - TriplyDB

CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection.

CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection.

http://www.wikidata.org/entity/Q37295552

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Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts Nonpathogenic simian immunodeficiency virus infections Double-negative T cells during HIV/SIV infections: potential pinch hitters in the T-cell lineup Natural SIV hosts: showing AIDS the door Intact type I Interferon production and IRF7 function in sooty mangabeys Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection T-Cell tropism of simian varicella virus during primary infection SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys.Factors associated with siman immunodeficiency virus transmission in a natural African nonhuman primate host in the wild.The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation Suppression of adaptive immune responses during primary SIV infection of sabaeus African green monkeys delays partial containment of viremia but does not induce disease.A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation Nonprogressive and progressive primate immunodeficiency lentivirus infections.Immune activation is associated with CD8 T cell interleukin-21 production in HIV-1-infected individuals.Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.Tularemia vaccines: recent developments and remaining hurdles.Pattern of SIVagm infection in patas monkeys suggests that host adaptation to simian immunodeficiency virus infection may result in resistance to infection and virus extinction.Homeostatic cytokines induce CD4 downregulation in African green monkeys independently of antigen exposure to generate simian immunodeficiency virus-resistant CD8αα T cells.Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques.Systems biology of natural simian immunodeficiency virus infections A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study HIV-associated chronic immune activation.Semen protects CD4+ target cells from HIV infection but promotes the preferential transmission of R5 tropic HIV Lentiviral Nef proteins manipulate T cells in a subset-specific manner Immunodeficiency lentiviral infections in natural and non-natural hosts.High cell-free virus load and robust autologous humoral immune responses in breast milk of simian immunodeficiency virus-infected african green monkeys.CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus.Reservoir host immune responses to emerging zoonotic viruses.Increased inherent intestinal granzyme B expression may be associated with SIV pathogenesis in Asian non-human primates.Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx).Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression.Cloning and analysis of sooty mangabey alternative coreceptors that support simian immunodeficiency virus SIVsmm entry independently of CCR5.Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates.Mucosal simian immunodeficiency virus transmission in African green monkeys: susceptibility to infection is proportional to target cell availability at mucosal sites Simian immunodeficiency virus-induced alterations in monocyte production of tumor necrosis factor alpha contribute to reduced immune activation in sooty mangabeys

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CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection.

http://www.wikidata.org/entity/Q37295552

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 14 June 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

CD4 downregulation by memory C ...... progressive SIVagm infection.

@en

CD4 downregulation by memory C ...... progressive SIVagm infection.

@nl

type

label

CD4 downregulation by memory C ...... progressive SIVagm infection.

@en

CD4 downregulation by memory C ...... progressive SIVagm infection.

@nl

prefLabel

CD4 downregulation by memory C ...... progressive SIVagm infection.

@en

CD4 downregulation by memory C ...... progressive SIVagm infection.

@nl

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Nature Medicine

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CD4 downregulation by memory C ...... progressive SIVagm infection.

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Coreen M Beaumier

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Jason M Brenchley

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John McGinty

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Levelle D Harris

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Nichole R Klatt

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Simoy Goldstein

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Sonya Whitted

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Vanessa M Hirsch

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P2860

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex

The CD40 antigen and its ligand

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR

AIDS as a zoonosis: scientific and public health implications

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients.

Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication.

Plateau levels of viremia correlate with the degree of CD4+-T-cell loss in simian immunodeficiency virus SIVagm-infected pigtailed macaques: variable pathogenicity of natural SIVagm isolates.

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879-885

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scholarly article

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10.1038/NM.1970

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8

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15

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Cristian Apetrei

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2009-06-14T00:00:00Z

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26291620

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19525963

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2723181

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