Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity.
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Sphingolipids in High Fat Diet and Obesity-Related DiseasesOverexpression of the adiponectin receptor AdipoR1 in rat skeletal muscle amplifies local insulin sensitivityLipotoxicity disrupts incretin-regulated human β cell connectivityThe impact of sphingosine kinase-1 in head and neck cancer.Sphingolipids in obesity, type 2 diabetes, and metabolic disease.Prosteatotic genes are associated with unsaturated fat suppression of saturated fat-induced hepatic steatosis in C57BL/6 mice.Sphingomyelinase stimulates oxidant signaling to weaken skeletal muscle and promote fatigue.Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity.Differential regulation of dihydroceramide desaturase by palmitate versus monounsaturated fatty acids: implications for insulin resistanceEffects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubesFactors to consider in using [U-C]palmitate for analysis of sphingolipid biosynthesis by tandem mass spectrometry.Sphingolipid metabolism, oxidant signaling, and contractile function of skeletal muscleSphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity.Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial functionSphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein ExpressionSphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes.Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes.Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties.Sphingosine kinase 1 is regulated by peroxisome proliferator-activated receptor α in response to free fatty acids and is essential for skeletal muscle interleukin-6 production and signaling in diet-induced obesity.Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function.Sphingosine 1-phosphate axis: a new leader actor in skeletal muscle biology.Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival.Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress.Diet-induced obesity impairs muscle satellite cell activation and muscle repair through alterations in hepatocyte growth factor signaling.A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress.Effect of plasma free fatty acid supply on the rate of ceramide synthesis in different muscle types in the rat.Probing de novo sphingolipid metabolism in mammalian cells utilizing mass spectrometry.Palmitoyl-ceramide accumulation with necrotic cell death in A549 cells, followed by a steep increase in sphinganine content.Sphingolipid regulators of cellular dysfunction in Type 2 diabetes mellitus: a systems overview.High Fat With High Sucrose Diet Leads to Obesity and Induces Myodegeneration
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Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Palmitate increases sphingosin ...... e kinase message and activity.
@en
Palmitate increases sphingosin ...... e kinase message and activity.
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type
label
Palmitate increases sphingosin ...... e kinase message and activity.
@en
Palmitate increases sphingosin ...... e kinase message and activity.
@nl
prefLabel
Palmitate increases sphingosin ...... e kinase message and activity.
@en
Palmitate increases sphingosin ...... e kinase message and activity.
@nl
P2093
P2860
P1476
Palmitate increases sphingosin ...... e kinase message and activity.
@en
P2093
Alfred H Merrill
Fahumiya Samad
Jacek Bielawski
L Ashley Cowart
P2860
P304
P356
10.1194/JLR.M800635-JLR200
P577
2009-04-15T00:00:00Z