Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling. - Wikidata - awgldk - TriplyDB

Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.

Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.

http://www.wikidata.org/entity/Q37302883

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Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells.Farnesoid X receptor, a novel proto-oncogene in non-small cell lung cancer, promotes tumor growth via directly transactivating CCND1.MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway.CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway Transmembrane-Bound IL-15-Promoted Epithelial-Mesenchymal Transition in Renal Cancer Cells Requires the Src-Dependent Akt/GSK-3β/β-Catenin Pathway.Emerging potential of natural products for targeting mucins for therapy against inflammation and cancer.Guggulsterone inhibits human cholangiocarcinoma Sk-ChA-1 and Mz-ChA-1 cell growth by inducing caspase-dependent apoptosis and downregulation of survivin and Bcl-2 expression.Cancer prevention and therapy through the modulation of the tumor microenvironment.Analysis of Important Gene Ontology Terms and Biological Pathways Related to Pancreatic Cancer.Pancreatic stellate cell: Pandora's box for pancreatic disease biology.Potential therapeutic targets of Guggulsterone in cancer Characterization of RNA editome in primary and metastatic lung adenocarcinomas.MUC4 mucin- a therapeutic target for pancreatic ductal adenocarcinoma.miR-216a may inhibit pancreatic tumor growth by targeting JAK2.Multidrug-resistant cancer cells and cancer stem cells hijack cellular systems to circumvent systemic therapies, can natural products reverse this?Guggulsterone and Its Role in Chronic Diseases.Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer.Downregulation of Piwil3 suppresses cell proliferation, migration and invasion in gastric cancer.ATM‑JAK‑PD‑L1 signaling pathway inhibition decreases EMT and metastasis of androgen‑independent prostate cancer.Emerging therapeutic potential of graviola and its constituents in cancers.IGF-1-induced MMP-11 expression promotes the proliferation and invasion of gastric cancer cells through the JAK1/STAT3 signaling pathway.Farnesoid X Receptor Activation Enhances Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases Subgroup analysis reveals molecular heterogeneity and provides potential precise treatment for pancreatic cancers Oxymatrine exhibits anti-tumor activity in gastric cancer through inhibition of IL-21R-mediated JAK2/STAT3 pathway

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Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.

http://www.wikidata.org/entity/Q37302883

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 03 August 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Guggulsterone decreases prolif ...... AK/STAT and Src/FAK signaling.

@en

Guggulsterone decreases prolif ...... AK/STAT and Src/FAK signaling.

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type

label

Guggulsterone decreases prolif ...... AK/STAT and Src/FAK signaling.

@en

Guggulsterone decreases prolif ...... AK/STAT and Src/FAK signaling.

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prefLabel

Guggulsterone decreases prolif ...... AK/STAT and Src/FAK signaling.

@en

Guggulsterone decreases prolif ...... AK/STAT and Src/FAK signaling.

@nl

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J.CANLET.2013.07.037

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Guggulsterone decreases prolif ...... AK/STAT and Src/FAK signaling.

@en

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Maneesh Jain

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Moorthy P Ponnusamy

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Muzafar A Macha

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Priya Pai

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Satyanarayana Rachagani

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Suprit Gupta

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Surinder K Batra

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P2860

Global cancer statistics

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism

FAK regulates biological processes important for the pathogenesis of cancer

Mucins in cancer: protection and control of the cell surface

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism.

14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in head and neck cancer cells.

MUC4 down-regulation reverses chemoresistance of pancreatic cancer stem/progenitor cells and their progenies

Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies

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166-177

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scholarly article

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10.1016/J.CANLET.2013.07.037

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2013-08-03T00:00:00Z

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255693146

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23920124

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3825785

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