c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism.
about
C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptorA phosphotyrosine displacement mechanism for activation of Src by PTPalphaCbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motilityCoordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeletonThe rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residueHic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinaseVav family proteins couple to diverse cell surface receptorsFibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteinsVav2 is required for cell spreadingDystroglycan, Tks5 and Src mediated assembly of podosomes in myoblastsActive site profiling reveals coupling between domains in SRC-family kinasesInteractions between the L1 cell adhesion molecule and ezrin support traction-force generation and can be regulated by tyrosine phosphorylation.CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migrationProteolysis of the docking protein HEF1 and implications for focal adhesion dynamicsProtein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesionPyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.P130Cas attenuates epidermal growth factor (EGF) receptor internalization by modulating EGF-triggered dynamin phosphorylationc-Src-null mice exhibit defects in normal mammary gland development and ERalpha signalingRoles of C-terminal Src kinase in the initiation and the termination of the high affinity IgE receptor-mediated signalingModulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionMultiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation eventsInhibition of N1-Src kinase by a specific SH3 peptide ligand reveals a role for N1-Src in neurite elongation by L1-CAM.Interaction between the SH3 domain of Src family kinases and the proline-rich motif of HTLV-1 p13: a novel mechanism underlying delivery of Src family kinases to mitochondria.Src family kinases are required for integrin but not PDGFR signal transduction.Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activitiesThe C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism.SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.v-Src SH3-enhanced interaction with focal adhesion kinase at beta 1 integrin-containing invadopodia promotes cell invasion.Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival.The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylationRequirement of a Src family kinase for initiating calcium release at fertilization in starfish eggs.Overexpression of C-terminal Src kinase homologous kinase suppresses activation of Lyn tyrosine kinase required for VLA5-mediated Dami cell spreading.The role of the Src homology domains in morphological transformation by v-srcRequirements for localization of p130cas to focal adhesions.Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs.Association between receptor protein-tyrosine phosphatase RPTPalpha and the Grb2 adaptor. Dual Src homology (SH) 2/SH3 domain requirement and functional consequences.Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.
P2860
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P2860
c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism.
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
c-Src enhances the spreading o ...... kinase-independent mechanism.
@ast
c-Src enhances the spreading o ...... kinase-independent mechanism.
@en
type
label
c-Src enhances the spreading o ...... kinase-independent mechanism.
@ast
c-Src enhances the spreading o ...... kinase-independent mechanism.
@en
prefLabel
c-Src enhances the spreading o ...... kinase-independent mechanism.
@ast
c-Src enhances the spreading o ...... kinase-independent mechanism.
@en
P356
P1433
P1476
c-Src enhances the spreading o ...... kinase-independent mechanism.
@en
P2093
P304
P356
10.1101/GAD.9.12.1505
P577
1995-06-01T00:00:00Z