A critical role for neutrophil elastase in experimental bullous pemphigoid
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Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoidMatrix metalloproteinases: old dogs with new tricksDiagnostic pathways and clinical significance of desquamative gingivitisThe IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsoneProteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen.Synergy between a plasminogen cascade and MMP-9 in autoimmune diseaseMechanisms of Autoantibody-Induced Pathology.The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitmentInnate immune cell-produced IL-17 sustains inflammation in bullous pemphigoid.Experimental models for the autoimmune and inflammatory blistering disease, Bullous pemphigoid.Dual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoidRole of saliva proteinase 3 in dental cariesNeutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells.A Pulmonary Perspective on GASPIDs: Granule-Associated Serine Peptidases of Immune Defense.Neutrophil serine proteases fine-tune the inflammatory responseBullous pemphigoid and neurodegenerative diseases: a study in a setting of a Central European university dermatology departmentConjunctival Neutrophils Predict Progressive Scarring in Ocular Mucous Membrane Pemphigoid.A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice.Autoimmunity-driven enzymatic remodeling of the dermal-epidermal junction in bullous pemphigoid and dermatitis herpetiformis.Pemphigoid diseases: pathogenesis, diagnosis, and treatment.Experiences with animal models of dermatitis herpetiformis: a review.Bullous pemphigoid: role of complement and mechanisms for blister formation within the lamina lucida.Signalling and targeted therapy of inflammatory cells in epidermolysis bullosa acquisita.Eosinophil localization to the basement membrane zone is autoantibody- and complement-dependent in a human cryosection model of bullous pemphigoid.Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophilsDipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis.Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoid.The pathophysiology of autoimmune blistering diseases.Differential roles for beta2 integrins in experimental autoimmune bullous pemphigoid.Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid.Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments.Anti-idiotypic Antibodies against BP-IgG Prevent Type XVII Collagen Depletion.Biomarkers related to bullous pemphigoid activity and outcome.Eosinophils as putative therapeutic targets in bullous pemphigoid.Elevated expression and release of tissue-type, but not urokinase-type, plasminogen activator after binding of autoantibodies to bullous pemphigoid antigen 180 in cultured human keratinocytes.
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A critical role for neutrophil elastase in experimental bullous pemphigoid
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2000
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A critical role for neutrophil elastase in experimental bullous pemphigoid
@en
A critical role for neutrophil elastase in experimental bullous pemphigoid.
@nl
type
label
A critical role for neutrophil elastase in experimental bullous pemphigoid
@en
A critical role for neutrophil elastase in experimental bullous pemphigoid.
@nl
prefLabel
A critical role for neutrophil elastase in experimental bullous pemphigoid
@en
A critical role for neutrophil elastase in experimental bullous pemphigoid.
@nl
P2093
P2860
P356
P1476
A critical role for neutrophil elastase in experimental bullous pemphigoid
@en
P2093
G J Giudice
R M Senior
S D Shapiro
S S Twining
P2860
P304
P356
10.1172/JCI3693
P407
P577
2000-01-01T00:00:00Z