Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications
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Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable proteinNew insights into estrogenic regulation of O6-methylguanine DNA-methyltransferase (MGMT) in human breast cancer cells: Co-degradation of ER-α and MGMT proteins by fulvestrant or O6-benzylguanine indicates fresh avenues for therapy.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.Identification of the Structural Features of Guanine Derivatives as MGMT Inhibitors Using 3D-QSAR Modeling Combined with Molecular Docking.BRCA2 affects the efficiency of DNA double-strand break repair in response to N-nitroso compounds with differing carcinogenic potentials.Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights.
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Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Degradation of BRCA2 in alkylt ...... and its clinical implications
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Degradation of BRCA2 in alkylt ...... and its clinical implications.
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Degradation of BRCA2 in alkylt ...... and its clinical implications
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Degradation of BRCA2 in alkylt ...... and its clinical implications.
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Degradation of BRCA2 in alkylt ...... and its clinical implications
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Degradation of BRCA2 in alkylt ...... and its clinical implications.
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Degradation of BRCA2 in alkylt ...... and its clinical implications
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Anthony E Pegg
Diana C Haines
Kajal Biswas
Natalia A Loktionova
Philipp Kaldis
Sergey G Kuznetsov
Shyam K Sharan
Sreenivas Kanugula
Srividya Swaminathan
Subha Philip
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P304
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10.1158/0008-5472.CAN-08-1179
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2008-12-01T00:00:00Z