TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. - Wikidata - awgldk - TriplyDB

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

http://www.wikidata.org/entity/Q37316068

about

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene Pathology, Molecular Genetics, and Epigenetics of Diffuse Intrinsic Pontine Glioma Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells.In vivo Mn-enhanced MRI for early tumor detection and growth rate analysis in a mouse medulloblastoma model.TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors Genetic landscape of extreme responders with anaplastic oligodendroglioma.BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma.TERT promoter mutations and telomere length in adult malignant gliomas and recurrences.Clinical Characteristics and Prognostic Significance of TERT Promoter Mutations in Cancer: A Cohort Study and a Meta-Analysis.A somatic reference standard for cancer genome sequencing.Genetic and molecular alterations across medulloblastoma subgroups Divergent clonal selection dominates medulloblastoma at recurrence Stop pulling my strings - what telomeres taught us about the DNA damage response.RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma.Duration of the pre-diagnostic interval in medulloblastoma is subgroup dependent.Telomerase promoter mutations in cancer: an emerging molecular biomarker?Medulloblastoma development: tumor biology informs treatment decisions Diffusely infiltrating astrocytomas: pathology, molecular mechanisms and markers.Intertumoral Heterogeneity within Medulloblastoma Subgroups.p53 and Meduloblastoma.An epigenetic gateway to brain tumor cell identity.Understanding TERT Promoter Mutations: A Common Path to Immortality.Medulloblastoma: Tumor Biology and Relevance to Treatment and Prognosis Paradigm.Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.Molecular pathology of paediatric central nervous system tumours.Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.Telomeres in cancer: tumour suppression and genome instability.TERT promoter mutations contribute to subset prognostication of lower-grade gliomas.The evolution of medulloblastoma therapy to personalized medicine.Association of Telomerase Reverse Transcriptase Promoter Mutations with the Prognosis of Glioma Patients: a Meta-Analysis.Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma.TERT promoter mutations and BRAF mutations are rare in sporadic, and TERT promoter mutations are absent in NF1-related malignant peripheral nerve sheath tumors.Medulloblastoma in adults: they're not just big kids.Characterisation of the changing genomic landscape of metastatic melanoma using cell free DNA.Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors.TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours.Epigenetic regulation in medulloblastoma.

P2860

Q26739925-CBBA9A16-3513-4306-AF03-6AB45E45BC59 Q26801528-7B369671-F57B-4BC4-A696-83773D5E43D1 Q27310060-DEDA01E6-B541-47B7-A3AC-A63994CFF900 Q27852966-23262537-1AD4-4713-9F27-E59F67C84357 Q30613404-1D93501E-88B2-4A0A-9884-0F521550C4D1 Q30618694-10268880-70EE-44BC-A172-63E2B3912418 Q33414576-5325E5E4-A07E-4E6C-AFE7-38E02D65396C Q33709979-E2A33994-A69D-4642-8236-197C967EDB26 Q33829209-1A2742CA-6DBA-4AE8-A90A-F6F3678AC48B Q35168770-647F3076-2853-42E8-9011-D52C39443F05 Q35833084-BACA76F5-2748-4CEA-9996-0F50AC31F1F3 Q35901458-AAD81FF9-2110-4BFA-AF26-8083B7A0773C Q35994200-6D4F80CD-F760-4FE1-8AA9-DF5EFE135843 Q36142459-04C3B3B3-BBBD-47DD-988B-EB97722DFCA1 Q37073617-9511D72C-B8D7-4F50-9D00-89411A77A486 Q37742751-3CE2D42F-0267-4684-9E41-D527485797E4 Q38194436-89EC8373-7C3B-47D6-AD52-B80863129AFF Q38194990-F2ED40BB-D0C4-4032-8B9D-ABA30E363E64 Q38232447-778AF23E-1C8C-4ABF-8E8D-8401FDE0A367 Q38376606-7A994315-E934-4908-9C9B-FF7C77685B8C Q38480437-E4FECAE8-4D7F-4B8A-9B51-BE6239D8D730 Q38671456-29369D41-F079-49C8-A822-C90A7B55B69A Q38673795-C5D93DF2-36F0-40AF-BFCD-6C87C2DBA5C0 Q38682159-96B59990-BFBF-4B71-92D2-EC956F3AB989 Q38760235-17A4FC4F-B545-4488-80AE-B5D1CC4B24B5 Q38791824-C99B73A1-EC9C-4E37-99FB-0EE82A8282B8 Q38874534-EA094B4C-56BF-4111-8294-F6D942328BDA Q38971961-5749F744-5943-4DC1-A61B-FC9E6D611841 Q38997020-8CB914C4-2C4A-4B91-8728-B2FF4541978D Q39016011-25068BCB-53AE-46B3-A743-5DE72F18D2B7 Q39150267-0D0DAD46-42F3-41E9-BD46-D44ED04328D6 Q39438064-8C937063-0843-4A65-BF20-7C97DF6D9AD5 Q40560920-1A2FBED0-7DF2-4C62-A6F4-8D3E48242511 Q41561910-FBD565A7-F36D-4E3C-9EC2-5383EE6FEA33 Q42205608-E4363FB3-D4A4-41D6-853C-C3DA8B957FCA Q42562593-4DD0EDB5-C69B-4594-B772-A74B9DF3AE1A Q42641203-BF886B46-9F92-4311-B985-1153EA9B2433 Q42746699-EE2A8496-F12D-4834-A0E1-E277ED54A27B Q43125817-B19260E2-15FA-4914-AB9C-D5FC041CF6B6 Q47900778-6683E852-5ADC-49F7-99BF-549097672411

P2860

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

http://www.wikidata.org/entity/Q37316068

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 31 October 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

@en

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

@nl

type

label

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

@en

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

@nl

prefLabel

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

@en

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

@nl

P1433

Q37316068-00A4B48C-4327-4FC0-96F5-79222D34FCA4

P1476

Q37316068-6AE6BCE7-98DE-41A7-872E-6CE4BFCF3FF5

P2093

Q37316068-00922D31-D0D9-4D58-81C5-C03415C4408F

Q37316068-0A4E47EF-134E-4737-8766-5A6550CBFA69

Q37316068-0B7A67F5-FD75-43F0-A370-4876F0624108

Q37316068-13AD5F8D-53D0-4A78-A678-75A836A31E4B

Q37316068-14F76C1C-7E76-4FFC-A180-85AC150994BA

Q37316068-18C39C54-C742-46F4-8960-1C3243EDC06A

Q37316068-2012947F-DADD-4E7B-8B92-2A7708CA3EC3

Q37316068-279BF548-4614-4699-8646-58B8A150660A

Q37316068-2C457192-DE0D-49A7-B5A8-A152CCB7213A

Q37316068-2D9427B3-07E2-48A5-AEBE-44182D2ECDEB

P2860

Q37316068-0329CE88-32AE-4A1F-A8B2-CFFB1693C5AB

Q37316068-1083F5BA-243B-44F3-848E-1BC98824FB66

Q37316068-11806ED0-FB73-4018-96A0-D4D1A15E850C

Q37316068-11A621F0-8FE1-41FA-BC02-963A984B344A

Q37316068-163EE99F-88E3-4623-B043-CAF269C84484

Q37316068-175AC9F8-B654-4A22-A4B7-51C725F3637E

Q37316068-1E623F0F-8B19-40C1-A0CE-6E133D3C7E1A

Q37316068-21AEC962-388C-49AA-9222-930D79C3DAEA

Q37316068-267E7231-B89F-4BC5-9A32-9F1271E8008A

Q37316068-26E6981C-9FD0-4390-9053-863B5A30CD28

P2888

Q37316068-98044251-4FF8-47A3-87AF-EF66324816DB

P304

Q37316068-1B901024-B6CF-449E-A2AC-924ABF5FA596

P31

Q37316068-7D8FBB5E-38D1-4501-9AB7-6FF34D7A7B6A

P356

Q37316068-C045C862-390A-4C42-9863-05A939E51A5C

P433

Q37316068-0FD3E336-B3F2-4757-A78B-ECA9EEA0545A

P478

Q37316068-8070BEBC-DBD6-46CE-AB3A-B767B120C42C

P50

Q37316068-0B83467E-90AD-424E-B6A4-C923E102BB30

Q37316068-0DF38D37-B7E5-443A-83E4-514D120B249F

Q37316068-1ACBF1AD-CBEE-4874-951D-B1880E94E46F

Q37316068-20492030-D9B3-43FE-9182-F53BE6D93E33

Q37316068-2508935B-D171-426B-B7EE-E049E3BF6377

Q37316068-2A69AAE7-B978-4EF8-8A39-E5716CC1E84F

Q37316068-2C039F10-F8DA-40CC-B812-207CF54265D2

Q37316068-2D926927-57F8-44EF-B671-3D3882F39BDE

Q37316068-393505D5-04A4-4E3D-8B5F-6B135A132B5A

Q37316068-39A4B0FF-57C1-4C78-A101-0F90696CF8FD

P577

Q37316068-1A175EE2-6ACA-4197-93CA-8E91688539B5

P5875

Q37316068-2A803D8E-9108-426D-9E68-8497159DFA90

P698

Q37316068-B454B051-E808-437F-8343-868B958C3CDC

P921

Q37316068-8E1AA6F2-6A73-4721-9CBB-B034A2602780

P932

Q37316068-DFF1E511-6B0B-4517-8E2E-DF2FA25CBA95

P356

S00401-013-1198-2

P1433

Acta Neuropathologica

P1476

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

@en

P2093

A Sorana Morrissy

http://www.w3.org/2001/XMLSchema#string

Adrian M Dubuc

http://www.w3.org/2001/XMLSchema#string

Ali G Saad

http://www.w3.org/2001/XMLSchema#string

Almos Klekner

http://www.w3.org/2001/XMLSchema#string

Andrey Korshunov

http://www.w3.org/2001/XMLSchema#string

Anne Jouvet

http://www.w3.org/2001/XMLSchema#string

Annie Huang

http://www.w3.org/2001/XMLSchema#string

Betty Luu

http://www.w3.org/2001/XMLSchema#string

Boleslaw Lach

http://www.w3.org/2001/XMLSchema#string

Carlos G Carlotti

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular subgroups of medulloblastoma: the current consensus

Dissecting the genomic complexity underlying medulloblastoma

The 2007 WHO classification of tumours of the central nervous system

Highly prevalent TERT promoter mutations in aggressive thyroid cancers.

TERT promoter mutations in primary and secondary glioblastomas.

Specific association of human telomerase activity with immortal cells and cancer

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

The genetic landscape of the childhood cancer medulloblastoma

P2888

s00401-013-1198-2

P304

917-929

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S00401-013-1198-2

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

126

http://www.w3.org/2001/XMLSchema#string

P50

Erwin G Van Meir

William A Weiss

Samer K Elbabaa

Stefan M Pfister

Andreas von Deimling

Michelle Fèvre-Montange

Vijay Ramaswamy

Ulrich Schüller

P577

2013-10-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

258204201

http://www.w3.org/2001/XMLSchema#string

P698

24174164

http://www.w3.org/2001/XMLSchema#string

P921

medulloblastoma

P932

3830749

http://www.w3.org/2001/XMLSchema#string