High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition.
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Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma.Venetoclax is effective in small cell lung cancers with high BCL-2 expression.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.Cell death-based treatment of neuroblastoma.The irreversible ERBB1/2/4 inhibitor neratinib interacts with the BCL-2 inhibitor venetoclax to kill mammary cancer cells.Pathways and mechanisms of venetoclax resistance.Recombinant Newcastle disease virus expressing human IFN-λ1 (rL-hIFN-λ1)-induced apoptosis of A549 cells is connected to endoplasmic reticulum stress pathways
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High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
High efficacy of the BCL-2 inh ...... ination with MCL-1 inhibition.
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High efficacy of the BCL-2 inhibitor ABT199
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type
label
High efficacy of the BCL-2 inh ...... ination with MCL-1 inhibition.
@en
High efficacy of the BCL-2 inhibitor ABT199
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prefLabel
High efficacy of the BCL-2 inh ...... ination with MCL-1 inhibition.
@en
High efficacy of the BCL-2 inhibitor ABT199
@nl
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High efficacy of the BCL-2 inh ...... ination with MCL-1 inhibition.
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Ellen M Westerhout
Evan E Santo
Huib N Caron
Ida van der Ploeg
Ilona J M den Hartog
Jan J Molenaar
Laurel T Bate-Eya
Linda Schild
M Emmy M Dolman
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P304
27946-27958
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10.18632/ONCOTARGET.8547
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P577
2016-04-01T00:00:00Z