Programmed anuclear cell death delimits platelet life span.
about
A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americansBH3 mimetics to improve cancer therapy; mechanisms and examplesCurrent challenges and novel treatment strategies in double hit lymphomasUnderstanding platelet generation from megakaryocytes: implications for in vitro-derived plateletsTargeting BCL2-Proteins for the Treatment of Solid TumoursBAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial poreThe BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer TherapeuticsTargeting the apoptosis pathway in hematologic malignanciesTime-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation ActivityAssociation of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic feverStructure-Guided Rescaffolding of Selective Antagonists of BCL-X LProtein degradation systems in plateletsDiscovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based designMitochondrial apoptosis and BH3 mimeticsExploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy CombinationProteasome function is required for platelet productionEfficient elimination of cancer cells by deoxyglucose-ABT-263/737 combination therapyMutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopeniaBM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivoAspirin delimits platelet life span by proteasomal inhibitionChemical parsing: Dissecting cell dependencies with a toolkit of selective BCL-2 family inhibitorsThe functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains.c-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xLHA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines.Zebrafish in hematology: sushi or science?Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.A numerical analysis model for the interpretation of in vivo platelet consumption data.Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice.Platelets, petechiae, and preservation of the vascular wallAn ENU-induced recessive mutation in Mpl leads to thrombocytopenia with overdominanceMutational inhibition of c-Myb or p300 ameliorates treatment-induced thrombocytopeniaRole of sialic acid for platelet life span: exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes.Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.Investigating caspases and other markers of apoptosis in ITP.Drug-induced hemolytic anemia and thrombocytopenia associated with alterations of cell membrane lipids and acanthocyte formation.Physiologic and pathologic changes of platelets in pregnancy.Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity.Transgenic, inducible RNAi in megakaryocytes and platelets in mice.Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors.BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.
P2860
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P2860
Programmed anuclear cell death delimits platelet life span.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Programmed anuclear cell death delimits platelet life span.
@ast
Programmed anuclear cell death delimits platelet life span.
@en
type
label
Programmed anuclear cell death delimits platelet life span.
@ast
Programmed anuclear cell death delimits platelet life span.
@en
prefLabel
Programmed anuclear cell death delimits platelet life span.
@ast
Programmed anuclear cell death delimits platelet life span.
@en
P2093
P50
P1433
P1476
Programmed anuclear cell death delimits platelet life span
@en
P2093
Adrienne A Hilton
Jamie I Fletcher
Janelle E Collinge
Priscilla N Kelly
P304
P356
10.1016/J.CELL.2007.01.037
P407
P50
P577
2007-03-01T00:00:00Z