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Rabconnectin-3 is a functional regulator of mammalian Notch signalingNon-canonical Notch signaling: emerging role and mechanismThe Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch SignallingPatterned cell adhesion associated with tissue deformations during dorsal closure in DrosophilaNotch ligand endocytosis: mechanistic basis of signaling activityEmbryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in miceT cell receptor triggering by force.Expression of notch family proteins in placentas from patients with early-onset severe preeclampsia.Endocytic internalization routes required for delta/notch signalingThe vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptorProtein homeostasis and aging: The importance of exquisite quality control.γ-secretase-dependent cleavage initiates notch signaling from the plasma membraneCurrent views on the role of Notch signaling and the pathogenesis of human leukemia.E(y)1/TAF9 mediates the transcriptional output of Notch signaling in Drosophila.Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst.dEHBP1 controls exocytosis and recycling of Delta during asymmetric divisionsOptical tweezers studies on Notch: single-molecule interaction strength is independent of ligand endocytosis.Integrins regulate epithelial cell differentiation by modulating Notch activity.Signaling endosomes: seeing is believing.Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks.Regulation of somatic myosin activity by protein phosphatase 1β controls Drosophila oocyte polarizationThe Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisionsRal GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activationThe H(+) vacuolar ATPase maintains neural stem cells in the developing mouse cortex.Cell biological regulation of division fate in vertebrate neuroepithelial cells.Competition in notch signaling with cis enriches cell fate decisions.An overview of notch signaling in adult tissue renewal and maintenance.Endothelial cells-targeted soluble human Delta-like 4 suppresses both physiological and pathological ocular angiogenesis.Notch signaling is antagonized by SAO-1, a novel GYF-domain protein that interacts with the E3 ubiquitin ligase SEL-10 in Caenorhabditis elegansLoss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis.Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling.Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor.Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling.The Abelson tyrosine kinase regulates Notch endocytosis and signaling to maintain neuronal cell fate in Drosophila photoreceptorsImpaired endolysosomal function disrupts Notch signalling in optic nerve astrocytesNumb regulates the balance between Notch recycling and late-endosome targeting in Drosophila neural progenitor cells.Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling.Expression of mutant CHMP2B, an ESCRT-III component involved in frontotemporal dementia, causes eye deformities due to Notch misregulation in Drosophila.S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development.Targeting Notch to target cancer stem cells.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Endocytic regulation of Notch signaling.
@en
Endocytic regulation of Notch signaling.
@nl
type
label
Endocytic regulation of Notch signaling.
@en
Endocytic regulation of Notch signaling.
@nl
prefLabel
Endocytic regulation of Notch signaling.
@en
Endocytic regulation of Notch signaling.
@nl
P2860
P1476
Endocytic regulation of Notch signaling.
@en
P2093
David Bilder
Mark E Fortini
P2860
P304
P356
10.1016/J.GDE.2009.04.005
P577
2009-05-15T00:00:00Z